D,L-1'-Acetoxychavicol acetate, NF-kappaB inhibitor (ab142417)

Overview

  • Product name

    D,L-1'-Acetoxychavicol acetate, NF-kappaB inhibitor
  • Description

    NF-κB inhibitor
  • Biological description

    NF-κB inhibitor, inhibits cell growth in tumor cells. Induces G0-G1 cell cycle arrest and enhances apoptosis. Antitumor agent. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    52946-22-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ohnishi R  et al. 1'-acetoxychavicol acetate inhibits adipogenesis in 3T3-L1 adipocytes and in high fat-fed rats. Am J Chin Med 40:1189-204 (2012). Read more (PubMed: 23227791) »
  • Ito K  et al. 1'-acetoxychavicol acetate is a novel nuclear factor kappaB inhibitor with significant activity against multiple myeloma in vitro and in vivo. Cancer Res 65:4417-24 (2005). Read more (PubMed: 15899834) »
  • Ichikawa H  et al. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. J Immunol 174:7383-92 (2005). Read more (PubMed: 15905586) »

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