D,L-erythro-PDMP, glucosylceramide synthase inhibitor isomer (ab144051)

Overview

  • Product name

    D,L-erythro-PDMP, glucosylceramide synthase inhibitor isomer
  • Description

    Erythro isomer of the glucosylceramide synthase inhibitor D,L-threo-PDMP
  • Biological description

    Erythro isomer of the glucosylceramide synthase inhibitor D,L-threo-PDMP (Asc 4022)

    See similar compounds
  • Purity

    > 98%
  • CAS Number

    109760-77-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    N-[(1S,2R)-1-Hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]decanamide hydrochloride
  • Molecular weight

    427.03
  • Molecular formula

    C23H38N2O3.HCl
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol and in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@@H](O)c2ccccc2
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Pannu R  et al. A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma. J Biol Chem 280:13742-51 (2005). Read more (PubMed: 15668227) »
  • Abe A  et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta 1299:333-41 (1996). Read more (PubMed: 8597588) »

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