D,L-threo-PDMP, Glucosylceramide synthase inhibitor (ab144022)

Overview

  • Product name

    D,L-threo-PDMP, Glucosylceramide synthase inhibitor
  • Description

    Glucosylceramide synthase inhibitor
  • Biological description

    Glucosylceramide synthase inhibitor. Antimalarial activity. Antileukemic activity in combination with tetrandrine (Asc 2464). Active in vitro.

    See similar compounds
  • Purity

    > 98%
  • CAS Number

    80938-69-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Chen B  et al. Effect of D, L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol and tetrandrine on the reversion of multidrug resistance in K562/A02 cells. Hematology 16:24-30 (2011). Read more (PubMed: 21269564) »
  • Lauer SA  et al. Sphingolipid synthesis as a target for chemotherapy against malaria parasites. Proc Natl Acad Sci U S A 92:9181-5 (1995). Read more (PubMed: 7568097) »
  • Radin NS Rationales for cancer chemotherapy with PDMP, a specific inhibitor of glucosylceramide synthase. Mol Chem Neuropathol 21:111-27 (0). Read more (PubMed: 8086032) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab144022.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up