• Product name

  • Description

    Rabbit polyclonal to DLC1
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within C terminal amino acids 1271 -1516 of Human DLC1 (Q96QB1).

  • Positive control

    • A549 and HepG2 cell lysates and Human Breast ca tissue.



Our Abpromise guarantee covers the use of ab126257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 171 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • Function

    Functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
  • Tissue specificity

    Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.
  • Sequence similarities

    Contains 1 Rho-GAP domain.
    Contains 1 SAM (sterile alpha motif) domain.
    Contains 1 START domain.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • ARHGAP 7 antibody
    • ARHGAP7 antibody
    • Deleted in liver cancer 1 antibody
    • Deleted in liver cancer 1 protein antibody
    • DLC 1 antibody
    • Dlc-1 antibody
    • DLC1 antibody
    • DLC1 Rho GTPase activating protein antibody
    • FLJ21120 antibody
    • HP antibody
    • HP protein antibody
    • KIAA1723 antibody
    • p122 RhoGAP antibody
    • RHG07_HUMAN antibody
    • Rho GTPase activating protein 7 antibody
    • Rho GTPase-activating protein 7 antibody
    • Rho type GTPase activating protein 7 antibody
    • Rho-type GTPase-activating protein 7 antibody
    • StAR related lipid transfer (START) domain containing 12 antibody
    • StAR related lipid transfer protein 12 antibody
    • StAR-related lipid transfer protein 12 antibody
    • STARD 12 antibody
    • StARD12 antibody
    • START domain containing protein 12 antibody
    • START domain-containing protein 12 antibody
    see all


  • Anti-DLC1 antibody (ab126257) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 171 kDa

    Gel concentration: 5%
  • ab126257, at 1/500, staining DLC1 in Human Breast ca tissue by immunohistochemistry [Paraffin Embedded Tissues (IHC-P).


This product has been referenced in:

  • Ye Y  et al. Exosomal miR-141-3p regulates osteoblast activity to promote the osteoblastic metastasis of prostate cancer. Oncotarget 8:94834-94849 (2017). Read more (PubMed: 29212270) »
  • Xiao P  et al. miR-429 promotes the proliferation of non-small cell lung cancer cells via targeting DLC-1. Oncol Lett 12:2163-2168 (2016). WB ; Human . Read more (PubMed: 27602157) »
See all 2 Publications for this product

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