Anti-DLC1 antibody - C-terminal (ab180697)
Key features and details
- Rabbit polyclonal to DLC1 - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
-
Product name
Anti-DLC1 antibody - C-terminal
See all DLC1 primary antibodies -
Description
Rabbit polyclonal to DLC1 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment within Human DLC1 (C terminal). The exact sequence is proprietary.
Database link: Q96QB1 -
General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
Applications
Our Abpromise guarantee covers the use of ab180697 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/2000. Predicted molecular weight: 171 kDa. |
Target
-
Function
Functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization. -
Tissue specificity
Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus. -
Sequence similarities
Contains 1 Rho-GAP domain.
Contains 1 SAM (sterile alpha motif) domain.
Contains 1 START domain. -
Cellular localization
Cytoplasm. - Information by UniProt
-
Database links
- Entrez Gene: 10395 Human
- Entrez Gene: 50768 Mouse
- Omim: 604258 Human
- SwissProt: Q96QB1 Human
- SwissProt: Q9R0Z9 Mouse
- Unigene: 134296 Human
- Unigene: 210875 Mouse
-
Alternative names
- ARHGAP 7 antibody
- ARHGAP7 antibody
- Deleted in liver cancer 1 antibody
see all
Images
-
Western blot - Anti-DLC1 antibody - C-terminal (ab180697)Anti-DLC1 antibody - C-terminal (ab180697) at 1/500 dilution + Mouse lung extract
Predicted band size: 171 kDa
Protocols
Datasheets and documents
References (2)
ab180697 has been referenced in 2 publications.
- de Vries S et al. Notochordal Cell Matrix As a Therapeutic Agent for Intervertebral Disc Regeneration. Tissue Eng Part A 25:830-841 (2019). PubMed: 29739272
- de Vries SAH et al. Notochordal cell matrix as a bioactive lubricant for the osteoarthritic joint. Sci Rep 8:8875 (2018). PubMed: 29891965
