Anti-Dlx1 antibody (ab126054)
Key features and details
- Rabbit polyclonal to Dlx1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Dlx1 antibody
See all Dlx1 primary antibodies -
Description
Rabbit polyclonal to Dlx1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Chicken, Cow
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Immunogen
Recombinant protein fragment, corresponding to a region within amino acids 1-205 of Human Dlx1 (P56177).
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Positive control
- U87-MG whole cell lysate.
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General notes
Keep as concentrated solutionThe Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126054 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 27 kDa.
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| Notes |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 27 kDa. |
Target
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Function
Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. -
Sequence similarities
Belongs to the distal-less homeobox family.
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 521806 Cow
- Entrez Gene: 1745 Human
- Entrez Gene: 13390 Mouse
- Entrez Gene: 296500 Rat
- Omim: 600029 Human
- SwissProt: P56177 Human
- SwissProt: Q64317 Mouse
- SwissProt: Q64202 Rat
see all -
Alternative names
- DII B antibody
- Distal less homeo box 1 antibody
- Distal less homeobox 1 antibody
see all
Images
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Western blot - Anti-Dlx1 antibody (ab126054)Anti-Dlx1 antibody (ab126054) at 1/3000 dilution + U87-MG whole cell lysate at 30 µg
Predicted band size: 27 kDa
12% SDS PAGE
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab126054 has been referenced in 2 publications.
- Sun B et al. MicroRNA-539 functions as a tumour suppressor in prostate cancer via the TGF-ß/Smad4 signalling pathway by down-regulating DLX1. J Cell Mol Med 23:5934-5948 (2019). PubMed: 31298493
- Weber A et al. Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1. Nat Commun 9:2929 (2018). WB ; Human . PubMed: 30050033