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Anti-Dlx1 antibody (ab126054)

  • Datasheet
  • SDS
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Western blot - Anti-Dlx1 antibody (ab126054)

    Key features and details

    • Rabbit polyclonal to Dlx1
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-Dlx1 antibody
      See all Dlx1 primary antibodies
    • Description

      Rabbit polyclonal to Dlx1
    • Host species

      Rabbit
    • Tested applications

      Suitable for: WBmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse, Rat, Chicken, Cow
    • Immunogen

      Recombinant protein fragment, corresponding to a region within amino acids 1-205 of Human Dlx1 (P56177).

    • Positive control

      • U87-MG whole cell lysate.
    • General notes

      Keep as concentrated solution

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
    • Storage buffer

      pH: 7.00
      Preservative: 0.01% Thimerosal (merthiolate)
      Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurology process
      • Neurogenesis
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Domain Families
      • Developmental Families
      • Other
      • Stem Cells
      • Hematopoietic Progenitors
      • Intracellular Molecules

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab126054 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB
    1/500 - 1/3000. Predicted molecular weight: 27 kDa.
    Notes
    WB
    1/500 - 1/3000. Predicted molecular weight: 27 kDa.

    Target

    • Function

      Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions.
    • Sequence similarities

      Belongs to the distal-less homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Cellular localization

      Nucleus.
    • Target information above from: UniProt accession P56177 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 521806 Cow
      • Entrez Gene: 1745 Human
      • Entrez Gene: 13390 Mouse
      • Entrez Gene: 296500 Rat
      • Omim: 600029 Human
      • SwissProt: P56177 Human
      • SwissProt: Q64317 Mouse
      • SwissProt: Q64202 Rat
      • Unigene: 407015 Human
      • Unigene: 4543 Mouse
      • Unigene: 475101 Mouse
      • Unigene: 59152 Rat
      see all
    • Alternative names

      • DII B antibody
      • Distal less homeo box 1 antibody
      • Distal less homeobox 1 antibody
      • Distal-less homeobox gene 1a antibody
      • Dlx 1 antibody
      • Dlx antibody
      • Dlx1 antibody
      • Dlx1 distal-less homeobox 1 antibody
      • DLX1_HUMAN antibody
      • Homeo box protein DLX1 antibody
      • Homeobox protein DLX 1 antibody
      • Homeobox protein DLX-1 antibody
      • Homeobox protein Dlx1a antibody
      • Homeodomain transcription factor DLX1 antibody
      • MGC189409 antibody
      • OTTHUMP00000082494 antibody
      • OTTHUMP00000082497 antibody
      • OTTMUSP00000014202 antibody
      • RP23-419H3.3 antibody
      see all

    Images

    • Western blot - Anti-Dlx1 antibody (ab126054)
      Western blot - Anti-Dlx1 antibody (ab126054)
      Anti-Dlx1 antibody (ab126054) at 1/3000 dilution + U87-MG whole cell lysate at 30 µg

      Predicted band size: 27 kDa



      12% SDS PAGE

    Protocols

    • Western blot protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (2)

    Publishing research using ab126054? Please let us know so that we can cite the reference in this datasheet.

    ab126054 has been referenced in 2 publications.

    • Sun B  et al. MicroRNA-539 functions as a tumour suppressor in prostate cancer via the TGF-ß/Smad4 signalling pathway by down-regulating DLX1. J Cell Mol Med 23:5934-5948 (2019). PubMed: 31298493
    • Weber A  et al. Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1. Nat Commun 9:2929 (2018). WB ; Human . PubMed: 30050033

    Customer reviews and Q&As

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