Overview

  • Product name

    Anti-Dlx6 antibody [EPR9474]
    See all Dlx6 primary antibodies
  • Description

    Rabbit monoclonal [EPR9474] to Dlx6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IP, Flow Cytmore details
    Unsuitable for: ICC or IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Dlx6 aa 1-100 (N terminal). The exact sequence is proprietary.

  • Positive control

    • HeLa, Jurkat, Saos-2 and 293T cell lysates; 293T cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab137079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 20 kDa.
IP 1/10 - 1/100.
Flow Cyt 1/10.
  • Application notes
    Is unsuitable for ICC or IHC-P.
  • Target

    • Sequence similarities

      Belongs to the distal-less homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Developmental stage

      First expressed in embryos at 8.5-9 days in facial and branchial arch mesenchyme, otic vesicles and frontonasal ectoderm around olfactory placodes, a day later expression is seen in the developing forebrain in primordia of the ganglionic eminence and ventral diencephalic regions. In day 12.5 embryos, expressed in the brain and bones, and also in all skeletal structures of midgestation embryos after the first cartilage formation, and expression progressively declines in both brain and skeleton in day 15 embryos.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • Distal less homeo box 6 antibody
      • Distal less homeobox 6 antibody
      • Distal less homeobox gene 6a antibody
      • DLX6 antibody
      • DLX6_HUMAN antibody
      • Homeobox protein DLX-6 antibody
      • MGC125282 antibody
      • MGC125283 antibody
      • MGC125284 antibody
      • MGC125285 antibody
      • OTTHUMP00000205294 antibody
      see all

    Images

    • All lanes : Anti-Dlx6 antibody [EPR9474] (ab137079) at 1/1000 dilution

      Lane 1 : HeLa cell lysates
      Lane 2 : Jurkat cell lysates
      Lane 3 : Saos-2 cell lysates
      Lane 4 : 293T cell lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 20 kDa

    • Flow cytometric analysis of permeabilized 293T cells labelling Dlx6 with ab137079 at 1/10 dilution (red) or a Rabbit IgG (negative) (green).

    References

    This product has been referenced in:

    • Rattanasopha S  et al. Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I. J Med Genet 51:817-23 (2014). WB ; Human . Read more (PubMed: 25332435) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab137079.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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