Overview

  • Product name

    DMNPE-caged Luciferin, D-Luciferin precursor
  • Description

    Cell-permeable D-Luciferin precursor. Bioluminescent luciferase substrate.
  • Biological description

    Cell-permeable D-Luciferin (ab143654) precursor. Bioluminescent luciferase substrate. Emits lights upon oxidative decarboxylation in the presence of ATP. Provides a signal for intracellular ATP in vivo.
  • Purity

    > 95%
  • CAS Number

    223920-67-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(4,5-Dimethoxy-2-nitrophenyl)ethyl (4S)-2-(6-oxo-1,3-benzothiazol-2-ylidene)-1,3-thiazolidine-4-carboxylate
  • Molecular weight

    489.52
  • Molecular formula

    C21H19N3O7S2
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(OC(=O)[C@@H]1N=C(SC1)c2nc3ccc(O)cc3s2)c4cc(OC)c(OC)cc4[N+]([O-])=O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • McCutcheon DC  et al. Rapid and scalable assembly of firefly luciferase substrates. Org Biomol Chem : (2014). Read more (PubMed: 25525906) »
  • Yang J & Thomason DB An easily synthesized, photolyzable luciferase substrate for in vivo luciferase activity measurement. Biotechniques 15:848-50 (1993). Read more (PubMed: 8267979) »
  • Zhang Y  et al. Influence of bioluminescence imaging dynamics by D-luciferin uptake and efflux mechanisms. Mol Imaging 11:499-506 (0). Read more (PubMed: 23084250) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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