Overview

  • Product name
    DMNQ, non-alkyiating redox cycling quinone
  • Description
    Cell-permeable non-alkyiating redox cycling quinone
  • Biological description
    Cell-permeable, non-alkylating redox cycling quinone. Generates superoxide production and induces cell proliferation, apoptosis and necrosis in vitro. Redox cycling agent. Active in vivo and in vitro.
  • Purity
    > 99%
  • CAS Number
    6956-96-3
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Parry JD  et al. Pivotal role for two electron reduction in 2,3-dimethoxy-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone metabolism and kinetics in vivo that prevents liver redox stress. Chem Res Toxicol 22:717-25 (2009). Read more (PubMed: 19338340) »
  • Seung SA  et al. The relative importance of oxidative stress versus arylation in the mechanism of quinone-induced cytotoxicity to platelets. Chem Biol Interact 113:133-44 (1998). Read more (PubMed: 9717514) »
  • Dypbukt JM  et al. Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines. J Biol Chem 269:30553-60 (1994). Read more (PubMed: 7982974) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab144626.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up