Overview

  • Product name

    DMPQ dihydrochloride, PDGFRbeta inhibitor
  • Description

    Potent and selective PDGFRβ inhibitor
  • Biological description

    Potent and selective β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) inhibitor (IC50 = 80 nM). Shows >100-fold selectivity over EGFR, PKA, PKC, p56 and erbB2.

    Also available in simple stock solutions (ab146732) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity

    > 99%
  • CAS Number

    1123491-15-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Dolle RE  et al. 5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase. J Med Chem 37:2627-9 (1994). Read more (PubMed: 8064792) »

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