Anti-DNA PKcs (phospho T2609) antibody [10B1] (ab18356)

Publishing research using ab18356? Please let us know so that we can cite the reference in this datasheet.

ab18356 has been referenced in 28 publications.

  • Liu X  et al. Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways. Radiother Oncol N/A:N/A (2018). PubMed: 29685705
  • Igarashi K  et al. An Approach to Elucidate NBS1 Function in DNA Repair Using Frequent Nonsynonymous Polymorphism in Wild Medaka (Oryzias latipes) Populations. PLoS One 12:e0170006 (2017). PubMed: 28107384
  • Bermudez-Hernandez K  et al. A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy. Sci Rep 7:14882 (2017). PubMed: 29093506
  • Zhu S  et al. Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining. Nucleic Acids Res 45:10583-10594 (2017). PubMed: 28985363
  • Megiorni F  et al. Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells. J Hematol Oncol 10:161 (2017). WB ; Human . PubMed: 28985758
  • Cristini A  et al. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res 44:1161-78 (2016). ICC/IF ; Human . PubMed: 26578593
  • Zhang H  et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS One 11:e0167454 (2016). WB, ICC/IF ; Human . PubMed: 27907109
  • Goglia AG  et al. Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors. Mol Cancer Ther 14:326-42 (2015). PubMed: 25512618
  • Hausmann C  et al. ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. Oncotarget 6:34592-605 (2015). PubMed: 26460618
  • Gustafsson AS  et al. Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair. Mutat Res 769:1-10 (2014). PubMed: 25771720
  • Staples CJ  et al. Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability. J Cell Sci 127:2910-9 (2014). PubMed: 24816561
  • Sahlberg SH  et al. The influence of AKT isoforms on radiation sensitivity and DNA repair in colon cancer cell lines. Tumour Biol 35:3525-34 (2014). WB, IF ; Human . PubMed: 24338765
  • Yue J  et al. Identification of the DNA repair defects in a case of Dubowitz syndrome. PLoS One 8:e54389 (2013). ICC/IF ; Human . PubMed: 23372718
  • Lu LY  et al. Regulation of the DNA damage response on male meiotic sex chromosomes. Nat Commun 4:2105 (2013). PubMed: 23812044
  • Chatterjee P  et al. Defective chromatin recruitment and retention of NHEJ core components in human tumor cells expressing a Cyclin E fragment. Nucleic Acids Res N/A:N/A (2013). PubMed: 24021630
  • Liu H  et al. A method for systematic mapping of protein lysine methylation identifies functions for HP1ß in DNA damage response. Mol Cell 50:723-35 (2013). PubMed: 23707759
  • Solier S  et al. Heat shock protein 90a (HSP90a), a substrate and chaperone of DNA-PK necessary for the apoptotic response. Proc Natl Acad Sci U S A 109:12866-72 (2012). ICC/IF . PubMed: 22753480
  • Moeller BJ  et al. Discovery of DNA repair inhibitors by combinatorial library profiling. Cancer Res 71:1816-24 (2011). WB, ICC/IF . PubMed: 21343400
  • Azad A  et al. Inhibition of DNA-dependent protein kinase induces accelerated senescence in irradiated human cancer cells. Mol Cancer Res 9:1696-707 (2011). ICC/IF . PubMed: 22009179
  • Solier S & Pommier Y MDC1 cleavage by caspase-3: a novel mechanism for inactivating the DNA damage response during apoptosis. Cancer Res 71:906-13 (2011). PubMed: 21148072
  • Solier S  et al. Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways. Mol Cell Biol 29:68-82 (2009). WB ; Human . PubMed: 18955500
  • Solier S & Pommier Y The apoptotic ring: a novel entity with phosphorylated histones H2AX and H2B and activated DNA damage response kinases. Cell Cycle 8:1853-9 (2009). ICC/IF ; Human . PubMed: 19448405
  • Forand A  et al. Similarities and differences in the in vivo response of mouse neonatal gonocytes and spermatogonia to genotoxic stress. Biol Reprod 80:860-73 (2009). ICC/IF ; Mouse . PubMed: 19144961
  • Merkle D  et al. Cellular dynamics of Ku: characterization and purification of Ku-eGFP. Chembiochem 9:1251-9 (2008). WB . PubMed: 18435448
  • Bencokova Z  et al. Molecular and cellular response of the most extensively used rodent glioma models to radiation and/or cisplatin. J Neurooncol 86:13-21 (2008). ICC/IF ; Rat . PubMed: 17611717
  • Zhang Y  et al. Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells. Cancer Lett 250:63-73 (2007). PubMed: 17095151
  • Lally BE  et al. Identification and biological evaluation of a novel and potent small molecule radiation sensitizer via an unbiased screen of a chemical library. Cancer Res 67:8791-9 (2007). PubMed: 17875720
  • Shimura T  et al. DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication. J Mol Biol 367:665-80 (2007). PubMed: 17280685


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