Overview

  • Product name

    Anti-DNA Polymerase theta antibody
    See all DNA Polymerase theta primary antibodies
  • Description

    Goat polyclonal to DNA Polymerase theta
  • Host species

    Goat
  • Species reactivity


    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to Human DNA Polymerase theta aa 1543-1555 (internal sequence). NP_955452.3.
    Sequence:

    DTHQQLTCSNDES


    Database link: O75417-1

  • Positive control

    • WB: Preliminary experiments in human brain (Cerebellum lysates) and in lysates of cell line HeLa gave no specific signal but low background (at antibody concentration up to 1 µg/ml).

Properties

Target

  • Function

    Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.
  • Tissue specificity

    Highly expressed in testis.
  • Sequence similarities

    Belongs to the DNA polymerase type-A family.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp781A0112 antibody
    • DNA polymerase eta antibody
    • DNA polymerase theta antibody
    • DPOLQ_HUMAN antibody
    • POLH antibody
    • POLQ antibody
    • Polymerase (DNA directed) theta antibody
    • PRO0327 antibody
    see all

References

ab239450 has not yet been referenced specifically in any publications.

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