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Rabbit polyclonal to DNAJC3
Predicted to work with:
Mouse, Rat, Cow, Pig
Recombinant fragment, corresponding to a region within amino acids 270-492 of Human DNAJC3 (UniProt Q13217).
293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 58 kDa.
Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
Contains 1 J domain.
Contains 9 TPR repeats.
The J domain mediates interaction with HSPA8.
Information by UniProt
DnaJ (Hsp40) homolog subfamily C member 3 antibody
DnaJ homolog subfamily C member 3 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"