Anti-DNase I antibody [6D5] (ab205567)

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Overview

  • Product name

    Anti-DNase I antibody [6D5]
    See all DNase I primary antibodies

  • Description

    Mouse monoclonal [6D5] to DNase I

  • Host species

    Mouse

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Cow
    Predicted to work with: Human

  • Immunogen

    Recombinant full length protein corresponding to Cow DNase I. Recombinant full length bovine DNaseI produced using CHO-based proprietary suspension cell line.
    Database link: P00639

  • Positive control

    • Recombinant bovine DNaseI expressed into the supernatant of CHO cell culture medium.

Properties

Applications

Our Abpromise guarantee covers the use of ab205567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.

WB: 0.1 to 0.2 μg/ml (bovine DNaseI) or 1 μg/ml (Human DNaseI)

Target

  • Function

    Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization.

  • Tissue specificity

    Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva.

  • Sequence similarities

    Belongs to the DNase I family.

  • Cellular localization

    Secreted. Nucleus envelope. Secretory protein, stored in zymogen granules and found in the nuclear envelope.
  • Information by UniProt

  • Database links

    • Alternative names

      • Deoxyribonuclease 1 antibody
      • Deoxyribonuclease I antibody
      • Deoxyribonuclease-1 antibody
      • Deoxyribonuclease1 antibody
      • DeoxyribonucleaseI antibody
      • DNAS1_HUMAN antibody
      • DNASE 1 antibody
      • DNase I antibody
      • DNase I lysosomal antibody
      • DNASE1 antibody
      • DNaseI antibody
      • DNL 1 antibody
      • DNL1 antibody
      • Dornase alfa antibody
      • DRNI antibody
      • FLJ38093 antibody
      • Human urine deoxyribonuclease I antibody
      see all

    Images

    • Western blot - Anti-DNase I antibody [6D5] (ab205567)
      Western blot - Anti-DNase I antibody [6D5] (ab205567)
      Anti-DNase I antibody [6D5] (ab205567) at 0.2 µg/ml + Recombinant bovine DNaseI expressed into the supernatant of CHO cell culture medium. at 10 µl

      Predicted band size: 31 kDa

    References

    ab205567 has not yet been referenced specifically in any publications.

    Publishing research using ab205567? Please let us know so that we can cite the reference in this datasheet.

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