Overview

  • Product name
    Anti-DNase I antibody
    See all DNase I primary antibodies
  • Description
    Mouse polyclonal to DNase I
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-282 of Human DNase I (NP_005214).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • DNASE1 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab167580 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 31 kDa.

Target

  • Function
    Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization.
  • Tissue specificity
    Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva.
  • Sequence similarities
    Belongs to the DNase I family.
  • Cellular localization
    Secreted. Nucleus envelope. Secretory protein, stored in zymogen granules and found in the nuclear envelope.
  • Information by UniProt
  • Database links
    • Alternative names
      • Deoxyribonuclease 1 antibody
      • Deoxyribonuclease I antibody
      • Deoxyribonuclease-1 antibody
      • Deoxyribonuclease1 antibody
      • DeoxyribonucleaseI antibody
      • DNAS1_HUMAN antibody
      • DNASE 1 antibody
      • DNase I antibody
      • DNase I lysosomal antibody
      • DNASE1 antibody
      • DNaseI antibody
      • DNL 1 antibody
      • DNL1 antibody
      • Dornase alfa antibody
      • DRNI antibody
      • FLJ38093 antibody
      • Human urine deoxyribonuclease I antibody
      see all

    Images

    • Western blot - Anti-DNase I antibody (ab167580)
      Western blot - Anti-DNase I antibody (ab167580)
      All lanes : Anti-DNase I antibody (ab167580) at 1 µg/ml

      Lane 1 : DNase I transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 15 µl per lane.

      Secondary
      All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

      Predicted band size: 31 kDa

    References

    ab167580 has not yet been referenced specifically in any publications.

    Publishing research using ab167580? Please let us know so that we can cite the reference in this datasheet.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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