Product nameDNase II peptide
See all DNase II proteins and peptides
Our Abpromise guarantee covers the use of ab8373 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
- Acid DNase
- Deoxyribonuclease 2
- Deoxyribonuclease 2 alpha
FunctionHydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Sequence similaritiesBelongs to the DNase II family.
modificationsGlycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.
- Information by UniProt
ab8373 has not yet been referenced specifically in any publications.