Overview

  • Product name

  • Description

    Rabbit polyclonal to Dnd1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human Dnd1 (internal sequence). The exact sequence is proprietary.
    Database link: Q8IYX4

  • Positive control

    • WB: Jurkat, Raji and NCI-H929 whole cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab226799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 39 kDa.

Target

  • Function

    RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration.
  • Sequence similarities

    Contains 2 RRM (RNA recognition motif) domains.
  • Cellular localization

    Nucleus. Cytoplasm. Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dead end homolog 1 (zebrafish) antibody
    • dead end homolog 1 antibody
    • Dead end protein antibody
    • Dead end protein homolog 1 antibody
    • Dead end, zebrafish, homolog, 1 antibody
    • DND microRNA-mediated repression inhibitor 1 antibody
    • dnd1 antibody
    • DND1_HUMAN antibody
    • MGC34750 antibody
    • RBMS4 antibody
    • RNA binding motif single stranded interacting protein 4 antibody
    • RNA-binding motif antibody
    • single-stranded-interacting protein 4 antibody
    • Ter antibody
    see all

Images

  • All lanes : Anti-Dnd1 antibody (ab226799) at 1/1000 dilution

    Lane 1 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell extract
    Lane 2 : Raji (human Burkitt's lymphoma cell line) whole cell extract
    Lane 3 : NCI-H929 whole cell extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 39 kDa



    10% SDS-PAGE gel.

References

ab226799 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab226799.
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