Key features and details
- Rabbit polyclonal to DNER
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab244355 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionActivator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
Tissue specificityExpressed in brain, spinal cord and adrenal gland.
Sequence similaritiesContains 10 EGF-like domains.
Contains 1 follistatin-like domain.
Cellular localizationCell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
- Information by UniProt
- bet antibody
- Brain EGF repeat-containing transmembrane protein antibody
- Bret antibody
Formalin-fixed, paraffin-embedded human cerebellum tissue stained for DNER with ab244355 at a 1/20 dilution in immunohistochemical analysis.
Formalin-fixed, paraffin-embedded human skeletal muscle tissue stained for DNER with ab244355 at a 1/20 dilution in immunohistochemical analysis. No positivity in myocytes as expected.
Formalin-fixed, paraffin-embedded human small intestine tissue stained for DNER with ab244355 at a 1/20 dilution in immunohistochemical analysis. No positivity in glandular cells as expected.
Formalin-fixed, paraffin-embedded human placenta tissue stained for DNER with ab244355 at a 1/20 dilution in immunohistochemical analysis. No positivity in trophoblastic cells as expected.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab244355 has not yet been referenced specifically in any publications.