Anti-Dnmt3b antibody - ChIP Grade (ab2851)

Rabbit polyclonal Dnmt3b antibody. Validated in WB, IP, IHC, ChIP, ICC/IF and tested in Mouse, Rat, Human. Cited in 48 publication(s). Independently reviewed in 5 review(s).

Publishing research using ab2851? Please let us know so that we can cite the reference in this datasheet.

ab2851 has been referenced in 49 publications.

  • Jin J  et al. Methylation-associated silencing of miR-128 promotes the development of esophageal cancer by targeting COX-2 in areas with a high incidence of esophageal cancer. Int J Oncol 54:644-654 (2019). PubMed: 30535495
  • Altshuler A  et al. RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells. Stem Cell Reports 10:1088-1101 (2018). WB ; Mouse . PubMed: 29456180
  • Pan XY  et al. DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis. Front Pharmacol 9:553 (2018). PubMed: 29892223
  • Liu X  et al. Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer. Biochim Biophys Acta N/A:N/A (2018). ChIP ; Human . PubMed: 29802960
  • Li J  et al. Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis. Mol Ther 26:1828-1839 (2018). PubMed: 29730197
  • Yang Y  et al. PSTPIP2 connects DNA methylation to macrophage polarization in CCL4-induced mouse model of hepatic fibrosis. Oncogene N/A:N/A (2018). PubMed: 29993036
  • Soni P  et al. Aflatoxin B1 induced multiple epigenetic modulators in human epithelial cell lines. Toxicon 151:119-128 (2018). PubMed: 30006306
  • Dong J  et al. Epigenetic silencing of microRNA-137 enhances ASCT2 expression and tumor glutamine metabolism. Oncogenesis 6:e356 (2017). ChIP . PubMed: 28692032
  • Chen S  et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res 45:1144-1158 (2017). WB ; Human . PubMed: 28180298
  • Yi Q  et al. Islet-1 induces the differentiation of mesenchymal stem cells into cardiomyocyte-like cells through the regulation of Gcn5 and DNMT-1. Mol Med Rep 15:2511-2520 (2017). WB, ChIP ; Mouse . PubMed: 28447752
  • Lloret-Llinares M  et al. Relationships between PROMPT and gene expression. RNA Biol 13:6-14 (2016). PubMed: 26574648
  • Peng H  et al. Higher methylation intensity induced by EBV LMP1 via NF-?B/DNMT3b signaling contributes to silencing of PTEN gene. Oncotarget 7:40025-40037 (2016). ChIP . PubMed: 27223069
  • Page A  et al. Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape. J Hepatol 64:661-73 (2016). PubMed: 26632634
  • Song G  et al. A novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells. Oncotarget 7:3144-57 (2016). PubMed: 26673819
  • Chen S  et al. Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy. Nucleic Acids Res N/A:N/A (2016). WB ; Human . PubMed: 27789696
  • Su RW  et al. Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility. Proc Natl Acad Sci U S A 113:2300-5 (2016). PubMed: 26858409
  • Brenner C  et al. The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent. Oncotarget 7:58939-58952 (2016). PubMed: 27449289
  • Yan B  et al. Micro-ribonucleic acid 29b inhibits cell proliferation and invasion and enhances cell apoptosis and chemotherapy effects of cisplatin via targeting of DNMT3b and AKT3 in prostate cancer. Onco Targets Ther 8:557-65 (2015). WB . PubMed: 25784815
  • Yang AN  et al. High-methionine diets accelerate atherosclerosis by HHcy-mediated FABP4 gene demethylation pathway via DNMT1 in ApoE(-/-) mice. FEBS Lett 589:3998-4009 (2015). WB . PubMed: 26606905
  • Li W  et al. Increased levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells. Gastroenterology 146:1714-26.e5 (2014). ChIP ; Human . PubMed: 24631494
  • Bittencourt D  et al. Role of distinct surfaces of the G9a ankyrin repeat domain in histone and DNA methylation during embryonic stem cell self-renewal and differentiation. Epigenetics Chromatin 7:27 (2014). PubMed: 25478012
  • Shen W  et al. Epigenetic modification of the leptin promoter in diet-induced obese mice and the effects of N-3 polyunsaturated Fatty acids. Sci Rep 4:5282 (2014). ChIP ; Mouse . PubMed: 24923522
  • Castro-Diaz N  et al. Evolutionally dynamic L1 regulation in embryonic stem cells. Genes Dev 28:1397-409 (2014). Human . PubMed: 24939876
  • Dunn J  et al. Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis. J Clin Invest 124:3187-99 (2014). WB, IHC-Fr ; Mouse . PubMed: 24865430
  • Bahar Halpern K  et al. Paradoxical Role of DNA Methylation in Activation of FoxA2 Gene Expression during Endoderm Development. J Biol Chem 289:23882-92 (2014). ChIP . PubMed: 25016019
  • Ito S  et al. Paired box 2 upregulates androgen receptor gene expression in androgen-independent prostate cancer. FEBS J 281:4506-18 (2014). PubMed: 25132193
  • Yang LH  et al. Axin gene methylation status correlates with radiosensitivity of lung cancer cells. BMC Cancer 13:368 (2013). PubMed: 23915259
  • Beckedorff FC  et al. The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation. PLoS Genet 9:e1003705 (2013). ChIP . PubMed: 23990798
  • Morano A  et al. Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene. Nucleic Acids Res N/A:N/A (2013). ChIP ; Human . PubMed: 24137009
  • Ehara T  et al. Role of DNA methylation in the regulation of lipogenic glycerol-3-phosphate acyltransferase 1 gene expression in the mouse neonatal liver. Diabetes 61:2442-50 (2012). ChIP . PubMed: 22721968
  • Selvakumar T  et al. Regulation of Human RNA Polymerase III Transcription by DNMT1 and DNMT3a DNA Methyltransferases. J Biol Chem 287:7039-50 (2012). PubMed: 22219193
  • Angrisano T  et al. Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells. Nucleic Acids Res 39:1993-2006 (2011). ChIP ; Human . PubMed: 20952403
  • Leonard S  et al. Epigenetic and Transcriptional Changes Which Follow Epstein-Barr Virus Infection of Germinal Center B Cells and Their Relevance to the Pathogenesis of Hodgkin's Lymphoma. J Virol 85:9568-77 (2011). PubMed: 21752916
  • Shah MY  et al. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Res 70:5840-50 (2010). PubMed: 20587527
  • Beyrouthy MJ  et al. High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors. Cancer Res 69:9360-6 (2009). PubMed: 19951990
  • Jeong S  et al. Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol 29:5366-76 (2009). PubMed: 19620278
  • Qin T  et al. Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines. Blood 113:659-67 (2009). WB ; Human . PubMed: 18931345
  • Kundakovic M  et al. The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Mol Pharmacol 75:342-54 (2009). ChIP ; Human . PubMed: 19029285
  • Kim MS  et al. DNA demethylation in hormone-induced transcriptional derepression. Nature 461:1007-12 (2009). ChIP ; Mouse . PubMed: 19829383
  • Palakurthy RK  et al. Epigenetic Silencing of the RASSF1A Tumor Suppressor Gene through HOXB3-Mediated Induction of DNMT3B Expression. Mol Cell 36:219-30 (2009). ChIP ; Human . PubMed: 19854132
  • Li Q  et al. Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms. Mol Pharmacol 76:1072-81 (2009). WB ; Human . PubMed: 19679824
  • Wu LP  et al. HDAC inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. Mol Cell Biol : (2008). WB ; Human . PubMed: 18332107
  • Park JH  et al. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest : (2008). ChIP ; Rat . PubMed: 18464933
  • Vincent A  et al. Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases. FASEB J : (2008). PubMed: 18492726
  • Fanelli M  et al. Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment. Oncogene 27:358-65 (2008). PubMed: 17653095
  • Kiskinis E  et al. RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes. EMBO J 26:4831-40 (2007). ChIP ; Mouse . PubMed: 17972916
  • Linhart HG  et al. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev 21:3110-22 (2007). PubMed: 18056424
  • Sato N  et al. The orphan nuclear receptor GCNF recruits DNA methyltransferase for Oct-3/4 silencing. Biochem Biophys Res Commun 344:845-51 (2006). WB, IP ; Mouse . PubMed: 16631596
  • Fazi F  et al. Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo. Oncogene 24:1820-30 (2005). PubMed: 15688037


Sign up