Question (45199) | Anti-Dnmt3L antibody (ab3493)

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Question

Hi,

I have a question about the epigenetics antibody https://www.abcam.com/index.html?datasheet=3493&tab=abreviews, anti-DNMT3L.

I would like to test DNMT3L levels in mouse by western blot –has this antibody been tested for cross-reactivity to DNMT3A and 3B? I couldn’t find any information about this on your website.

Many thanks,

Answer

Thank you for your inquiry.
I can confirm that it was not experimentally tested if this antibody shows any cross-reaction with the proteins DNMT3A and/or DNMT3B.
After performing a short BLAST search with the antigen, it is very unlikely that the antibody cross-reacts.
The BLAST search did not bring up these proteins in any species, but only showed DNMT3L proteins from different species.
I hope this information is helpful and wish you good luck with your research.

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