Key features and details
- Mouse polyclonal to DOCK7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DOCK7 antibody
See all DOCK7 primary antibodies
DescriptionMouse polyclonal to DOCK7
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Protein fragment corresponding to amino acids 1-624 of full length human DOCK7 protein (AAH16392.1).
- DOCK7 transfected 293T lysate.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.4
Constituent: 2.68% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab71858 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).|
RelevanceDOCK7 functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. It does not have a GEF activity for CDC42. It is required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
Cellular localizationCell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
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ab71858 has not yet been referenced specifically in any publications.