Overview

  • Product name

  • Description

    Mouse polyclonal to DOCK7
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Protein fragment corresponding to amino acids 1-624 of full length human DOCK7 protein (AAH16392.1).

  • Positive control

    • DOCK7 transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab71858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).

Target

  • Relevance

    DOCK7 functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. It does not have a GEF activity for CDC42. It is required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
  • Cellular localization

    Cell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
  • Database links

  • Alternative names

    • 3110056M06Rik antibody
    • dedicator of cytokinesis 7 antibody
    • Dedicator of cytokinesis protein 7 antibody
    • Gm430 antibody
    • KIAA1771 antibody
    • MGC189434 antibody
    • mKIAA1771 antibody
    • RP23 329P19.2 antibody
    • ZIR2 antibody
    see all

Images

  • All lanes : Anti-DOCK7 antibody (ab71858) at 1/500 dilution

    Lane 1 : DOCK7 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    All lanes : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size: 72 kDa
    Observed band size: 72 kDa

References

ab71858 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer

I am very pleased to hear you would like to test ab71858 in mouse. This code will give you a discount off your next order before the expiration date. To redeem this offer, please submit an Abreview for mouse and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active. For more information on how to submit an Abreview, please visit the site: https://www.abcam.com/Abreviews.

Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: https://www.abcam.com/abtrial.

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