Key features and details
- Rabbit polyclonal to Dopamine Transporter (phospho T53)
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-Dopamine Transporter (phospho T53) antibody
See all Dopamine Transporter primary antibodies
DescriptionRabbit polyclonal to Dopamine Transporter (phospho T53)
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Rat
Synthetic peptide within Rat Dopamine Transporter (phospho T53) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
Database link: P23977
- Rat caudate lysate.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.50
Constituents: 0.24% HEPES, 0.88% Sodium chloride, 0.01% BSA, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab183486 was prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
Our Abpromise guarantee covers the use of ab183486 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 68 kDa.|
FunctionAmine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Involvement in diseaseDefects in SLC6A3 are the cause of dystonia-parkinsonism infantile (DYTPRI) [MIM:613135]. It is a neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs.
Sequence similaritiesBelongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
- Information by UniProt
- DA transporter antibody
- DAT 1 antibody
- DAT antibody
ab183486 has been referenced in 1 publication.
- Foster JD et al. Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux. J Biol Chem 287:29702-12 (2012). PubMed: 22722938