Doripenem monohydrate, Ultra-broad spectrum carbapenem antibiotic (ab143392)

Overview

  • Product name

    Doripenem monohydrate, Ultra-broad spectrum carbapenem antibiotic
  • Description

    Ultra-broad spectrum carbapenem antibiotic
  • Purity

    > 98%
  • CAS Number

    364622-82-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate
  • Molecular weight

    438.52
  • Molecular formula

    C15H24N4O6S2.H2O
  • PubChem identifier

    636377
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C2C(C(=O)N2C(=C1SC3CC(NC3)CNS(=O)(=O)N)C(=O)O)C(C)O.O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Hagihara M  et al. KPC presence in Pseudomonas aeruginosa has minimal impact on the in vivo efficacy of carbapenem therapy. Antimicrob Agents Chemother 57:1086-8 (2013). Read more (PubMed: 23254422) »
  • Soon RL  et al. Pharmacodynamic variability beyond that explained by MICs. Antimicrob Agents Chemother 57:1730-5 (2013). Read more (PubMed: 23357773) »
  • Cordillot M  et al. In Vitro Cross-Linking of Mycobacterium tuberculosis Peptidoglycan by L,D-Transpeptidases and Inactivation of These Enzymes by Carbapenems. Antimicrob Agents Chemother 57:5940-5 (2013). Read more (PubMed: 24041897) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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