Doxycycline hyclate, matrix metalloprotease inhibitor (ab141091)
Key features and details
- Synthetic tetracycline; matrix metalloprotease inhibitor
- CAS Number: 24390-14-5
- Purity: > 97%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Doxycycline hyclate, matrix metalloprotease inhibitor -
Description
Synthetic tetracycline; matrix metalloprotease inhibitor -
Purity
> 97% -
CAS Number
24390-14-5 -
Chemical structure
Properties
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Chemical name
(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hyclate -
Molecular weight
512.94 -
Molecular formula
C22H24N2O8.HCl.0.5C2H5OH.0.5H2O -
PubChem identifier
54686183 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.Cl.O.CCO.NC(=O)C=3C(=O)[C@@]4(O)C(O)=C2C(=O)c1c(O)cccc1[C@H](C)[C@H]2[C@H](O)[C@H]4[C@H](N(C)C)C=3O.NC(=O)C=3C(=O)[C@@]4(O)C(O)=C2C(=O)c1c(O)cccc1[C@H](C)[C@H]2[C@H](O)[C@H]4[C@@H](C=3O)N(C)C -
Source
Synthetic
Associated products
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Related Products
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (7)
ab141091 has been referenced in 7 publications.
- Jansen KI et al. A live-cell marker to visualize the dynamics of stable microtubules throughout the cell cycle. J Cell Biol 222:N/A (2023). PubMed: 36880745
- Chang CC et al. Molecular crowding facilitates bundling of IMPDH polymers and cytoophidium formation. Cell Mol Life Sci 79:420 (2022). PubMed: 35833994
- Meiring JCM et al. Opto-katanin, an optogenetic tool for localized, microtubule disassembly. Curr Biol 32:4660-4674.e6 (2022). PubMed: 36174574
- Quatredeniers M et al. The renal inflammatory network of nephronophthisis. Hum Mol Genet 31:2121-2136 (2022). PubMed: 35043953
- Nijenhuis W et al. An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol 219:N/A (2020). PubMed: 32328628
- Viau A et al. Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol 31:1035-1049 (2020). PubMed: 32238474
- Pan J et al. Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas. Cancer Res 80:2722-2736 (2020). PubMed: 32332020