Key features and details
- Synthetic tetracycline; matrix metalloprotease inhibitor
- CAS Number: 24390-14-5
- Purity: > 97%
- Soluble in water to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameDoxycycline hyclate, matrix metalloprotease inhibitor
DescriptionSynthetic tetracycline; matrix metalloprotease inhibitor
Synthetic tetracycline; matrix metalloprotease (MMP) inhibitor. Inhibits tumour growth, suppresses cell proliferation and induces apoptosis in vitro and in vivo.
Chemical name(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hyclate
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141091 has been referenced in 1 publication.
- Nijenhuis W et al. An optimized toolbox for the optogenetic control of intracellular transport. J Cell Biol 219:N/A (2020). PubMed: 32328628