Overview

  • Product name

  • Description

    Rabbit polyclonal to DP2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chicken, Xenopus laevis
  • Immunogen

    Recombinant fragment, corresponding to a region within internal sequence amino acids 17-178 of Human DP2 (Q14188).

  • Positive control

    • WB: PC3 and Mouse muscle whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab155246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 49 kDa.

Target

  • Function

    Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
  • Tissue specificity

    High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
  • Sequence similarities

    Belongs to the E2F/DP family.
  • Post-translational
    modifications

    Ser-24 is probably phosphorylated by CDK2.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • DP2 antibody
    • E2F dimerization partner 2 antibody
    • Tfdp2 antibody
    • TFDP2_HUMAN antibody
    • Transcription factor Dp 2 antibody
    • Transcription factor Dp-2 antibody
    see all

Images

  • Anti-DP2 antibody (ab155246) at 1/1000 dilution + Mouse muscle whole cell lysate at 50 µg

    Predicted band size: 49 kDa



    10% SDS PAGE
  • Anti-DP2 antibody (ab155246) at 1/1000 dilution + PC-3 whole cell lysate at 30 µg

    Predicted band size: 49 kDa



    10% SDS PAGE

References

ab155246 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab155246.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up