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  1. Link

    dpdpe-delta-opioid-receptor-agonist-ab120675.pdf

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Neuroscience Neurotransmission Receptors / Channels GPCR Opioid Receptors
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DPDPE, delta opioid receptor agonist (ab120675)

  • Datasheet
  • SDS
  • COA
Submit a review Submit a question References (2)

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Chemical Structure - DPDPE, delta opioid receptor agonist (ab120675)

    Key features and details

    • Potent, selective δ opioid receptor agonist
    • CAS Number: 88373-73-3
    • Purity: > 95%
    • Soluble in water to 1 mg/ml
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      DPDPE, delta opioid receptor agonist
    • Description

      Potent, selective δ opioid receptor agonist
    • Alternative names

      • [D-Pen2,5]Enkephalin
    • Biological description

      Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.

    • Purity

      > 95%
    • CAS Number

      88373-73-3
    • Chemical structure

      Chemical Structure

    Properties

    • Molecular weight

      645.79
    • Molecular formula

      C30H39N5O7S2
    • Sequence

      YXGFX (Modifications: X-2 = D-Pen; X-5 = D-Pen; Disulfide bonds: 2-5)
    • Storage instructions

      Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in water to 1 mg/ml
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • Source

      Synthetic

    • Research areas

      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • GPCR
      • Opioid Receptors
      • Biochemicals
      • Product Range
      • Just Add Water
      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Biochemicals
      • Chemical Type
      • Bioactive peptides
      • Biochemicals
      • Pharmacology
      • Receptors & Transporters
      • Opioids
      • δ
      • Agonists
      • Biochemicals
      • Research Area
      • Addiction
      • Opioids
      • δ
      • agonists
      • Biochemicals
      • Research Area
      • Pain & inflammation
      • Opioids
      • δ
      • agonists

    Images

    • Chemical Structure - DPDPE, delta opioid receptor agonist (ab120675)
      Chemical Structure - DPDPE, delta opioid receptor agonist (ab120675)
      2D chemical structure image of ab120675, DPDPE, delta opioid receptor agonist

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download
    • COA

    References (2)

    Publishing research using ab120675? Please let us know so that we can cite the reference in this datasheet.

    ab120675 has been referenced in 2 publications.

    • Hall EA  et al. PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Am J Hum Genet 100:706-724 (2017). PubMed: 28413018
    • Bull FA  et al. Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by ß-arrestin2 and c-Src. Sci Rep 7:9969 (2017). PubMed: 28855588

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