DPDPE, delta opioid receptor agonist (ab120675)
- Datasheet
- References (2)
Overview
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Product name
DPDPE, delta opioid receptor agonist -
Description
Potent, selective δ opioid receptor agonist -
Alternative names
- [D-Pen2,5]Enkephalin
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Biological description
Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration. -
Purity
> 95% -
CAS Number
88373-73-3 -
Chemical structure
Properties
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Molecular weight
645.79 -
Molecular formula
C30H39N5O7S2 -
Sequence
YXGFX (Modifications: X-2 = D-Pen; X-5 = D-Pen; Disulfide bonds: 2-5) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 1 mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
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Research areas
References
This product has been referenced in:
- Chen C & Pollack GM Blood-brain disposition and antinociceptive effects of -D-penicillamine2,5-enkephalin in the mouse. J Pharmacol Exp Ther 283:1151-9 (1997). Read more (PubMed: 9399988) »
- Raynor K et al. Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Mol Pharmacol 45:330-4 (1994). Read more (PubMed: 8114680) »
