Overview

  • Product name

  • Description

    Rabbit polyclonal to DPEP1/MDP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human DPEP1/MDP aa 136-247.

  • Positive control

    • U-251 MG, Human Plasma and Human Tonsil lysates; Human kidney tissue
  • General notes

     This product was previously labelled as DPEP1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab121380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
  • Sequence similarities

    Belongs to the peptidase M19 family.
  • Cellular localization

    Apical cell membrane. Cell projection > microvillus membrane. Brush border membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dehydropeptidase-I antibody
    • Dipeptidase 1 (renal) antibody
    • Dipeptidase 1 antibody
    • DPEP1 antibody
    • DPEP1_HUMAN antibody
    • hRDP antibody
    • MBD1 antibody
    • MDP antibody
    • Microsomal dipeptidase antibody
    • RDP antibody
    • Renal dipeptidase antibody
    see all

Images

  • Immunocytochemistry/immunofluorescence analysis of HepG2 cells labelling DPEP1/MDP with ab121380 shows positive staining in the nucleus and cell junctions.

  • ab121380 staining DPEP1/MDP in Paraffin-emebedded Human kidney tissue by Immunohistochemistry.

References

ab121380 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab121380.
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