Overview

  • Product name

    Anti-DPP10 antibody - Extracellular domain
    See all DPP10 primary antibodies
  • Description

    Rabbit polyclonal to DPP10 - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Dog, Pig, Monkey, Gorilla
  • Immunogen

    Synthetic peptide within Human DPP10. The exact sequence is proprietary. Synthetic peptide corresponds to 14 amino acids of the extracellular domain. (NCBI Accession No. NP_065919.2)
    Database link: Q8N608

  • Positive control

    • Human brain tissue m(cerebellum Purkinje neurons).

Properties

Applications

Our Abpromise guarantee covers the use of ab188820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.
  • Tissue specificity

    Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands.
  • Involvement in disease

    Genetic variations in DPP10 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
  • Sequence similarities

    Belongs to the peptidase S9B family. DPPIV subfamily.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Dipeptidyl peptidase 10 antibody
    • Dipeptidyl peptidase 10 non functional antibody
    • Dipeptidyl peptidase IV related protein 3 antibody
    • Dipeptidyl peptidase IV-related protein 3 antibody
    • Dipeptidyl peptidase like protein 2 antibody
    • Dipeptidyl peptidase X antibody
    • Dipeptidyl peptidase-like protein 2 antibody
    • Dipeptidylpeptidase 10 antibody
    • DPL 2 antibody
    • DPL2 antibody
    • DPP 10 antibody
    • DPP X antibody
    • Dpp10 antibody
    • DPP10_HUMAN antibody
    • DPPY antibody
    • DPRP 3 antibody
    • DPRP-3 antibody
    • DPRP3 antibody
    • Inactive dipeptidyl peptidase 10 antibody
    • KIAA1492 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue, labeling DPP10 using ab188820 at 10 µg/ml.

References

ab188820 has not yet been referenced specifically in any publications.

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