Anti-DR3/LARD antibody (ab8411)
Key features and details
- Rabbit polyclonal to DR3/LARD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DR3/LARD antibody
See all DR3/LARD primary antibodies -
Description
Rabbit polyclonal to DR3/LARD -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human DR3/LARD aa 398-417 (C terminal).
(Peptide available asab8443) -
Positive control
- Jurkat total cell lysate A 59 kDa band should bedetected.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Light chain type
unknown -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab8411 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 59 kDa.
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 59 kDa. |
Target
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Function
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. -
Tissue specificity
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8718 Human
- Omim: 603366 Human
- SwissProt: Q93038 Human
- Unigene: 462529 Human
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Alternative names
- Apo 3 antibody
- Apo-3 antibody
- Apo3 antibody
see all
Images
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Anti-DR3/LARD antibody (ab8411) at 1/500 dilution + Jurkat total cell lysate
Observed band size: 59 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab8411 has not yet been referenced specifically in any publications.