Anti-DR3/LARD antibody [JD3] (ab234187)

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Overview

  • Product name

    Anti-DR3/LARD antibody [JD3]
    See all DR3/LARD primary antibodies

  • Description

    Mouse monoclonal [JD3] to DR3/LARD

  • Host species

    Mouse

  • Tested applications

    Suitable for: Flow Cytmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Fusion protein corresponding to Human DR3/LARD.
    Database link: Q93038

  • Positive control

    • Flow Cytometry: DR3/LARD-transfected HEK-293 cells.

  • General notes

     This product was previously labelled as DR3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab234187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Target

  • Function

    Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.

  • Tissue specificity

    Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.

  • Sequence similarities

    Contains 1 death domain.
    Contains 4 TNFR-Cys repeats.

  • Post-translational
    modifications

    Glycosylated.

  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • Apo 3 antibody
      • Apo-3 antibody
      • Apo3 antibody
      • Apoptosis inducing receptor AIR antibody
      • Apoptosis inducing receptor antibody
      • Apoptosis mediating receptor antibody
      • Apoptosis mediating receptor DR 3 antibody
      • Apoptosis mediating receptor DR3 antibody
      • Apoptosis mediating receptor TRAMP antibody
      • Apoptosis-inducing receptor AIR antibody
      • Apoptosis-mediating receptor DR3 antibody
      • Apoptosis-mediating receptor TRAMP antibody
      • DDR 3 antibody
      • DDR3 antibody
      • Death domain receptor 3 antibody
      • Death domain receptor 3 soluble form antibody
      • Death receptor 3 antibody
      • Death receptor beta antibody
      • DR 3 antibody
      • DR3 antibody
      • LARD antibody
      • Lymphocyte associated receptor of death antibody
      • Lymphocyte-associated receptor of death antibody
      • Protein WSL antibody
      • Protein WSL-1 antibody
      • TNF receptor superfamily member 25 antibody
      • TNFR25 antibody
      • TNFRSF 12 antibody
      • TNFRSF 25 antibody
      • TNFRSF12 antibody
      • TNFRSF12, formerly antibody
      • TNFRSF25 antibody
      • TNR25_HUMAN antibody
      • TR 3 antibody
      • TR3 antibody
      • TRAMP antibody
      • Translocating chain association membrane protein antibody
      • Tumor necrosis factor receptor superfamily member 12 antibody
      • Tumor necrosis factor receptor superfamily member 25 antibody
      • Tumor necrosis factor receptor superfamily, member 12 (translocating chain association membrane protein) antibody
      • Tumor necrosis factor receptor superfamily, member 12, formerly antibody
      • WSL 1 antibody
      • WSL antibody
      • WSL LR antibody
      • WSL protein antibody
      • WSL1 antibody
      • WSL1 protein antibody
      • WSLLR antibody
      see all

    Images

    • Flow Cytometry - Anti-DR3/LARD antibody [JD3] (ab234187)
      Flow Cytometry - Anti-DR3/LARD antibody [JD3] (ab234187)

      Flow cytometric analysis of DR3/LARD-transfected (red) and non-transfected HEK-293 (human epithelial cell line from embryonic kidney) (black) cells labeling DR3/LARD with ab234187.

    References

    ab234187 has not yet been referenced specifically in any publications.

    Publishing research using ab234187? Please let us know so that we can cite the reference in this datasheet.

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