Anti-DR3/LARD antibody [JD3] (ab234187)
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- References
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Overview
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Product name
Anti-DR3/LARD antibody [JD3]
See all DR3/LARD primary antibodies -
Description
Mouse monoclonal [JD3] to DR3/LARD -
Host species
Mouse -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein corresponding to Human DR3/LARD.
Database link: Q93038 -
Positive control
- Flow Cytometry: DR3/LARD-transfected HEK-293 cells.
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General notes
This product was previously labelled as DR3
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.0975% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Purity > 95% (by SDS-PAGE). -
Clonality
Monoclonal -
Clone number
JD3 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab234187 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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Flow Cyt | Use at an assay dependent concentration. |
Target
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Function
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. -
Tissue specificity
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8718 Human
- Omim: 603366 Human
- SwissProt: Q93038 Human
- Unigene: 462529 Human
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Alternative names
- Apo 3 antibody
- Apo-3 antibody
- Apo3 antibody
see all
Images
Datasheets and documents
References
ab234187 has not yet been referenced specifically in any publications.