Anti-DR3/LARD antibody - N-terminal (ab188628)
Key features and details
- Rabbit polyclonal to DR3/LARD - N-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DR3/LARD antibody - N-terminal
See all DR3/LARD primary antibodies -
Description
Rabbit polyclonal to DR3/LARD - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse
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Immunogen
Synthetic peptide corresponding to Human DR3/LARD aa 25-40 (N terminal).
Sequence:QGGTRS PRCDCAGDFH
Database link: Q93038 -
Positive control
- Jurkat cell lysate; Human prostate tissue.
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General notes
This product was previously labelled as DR3
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Ion Exchange Chromatography -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab188628 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/1000. Predicted molecular weight: 45 kDa. | |
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. -
Tissue specificity
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8718 Human
- Entrez Gene: 85030 Mouse
- Omim: 603366 Human
- SwissProt: Q93038 Human
- Unigene: 462529 Human
- Unigene: 101198 Mouse
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Alternative names
- Apo 3 antibody
- Apo-3 antibody
- Apo3 antibody
see all
Images
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Western blot - Anti-DR3/LARD antibody - N-terminal (ab188628)Anti-DR3/LARD antibody - N-terminal (ab188628) at 1/1000 dilution + Jurkat cell lysate
Predicted band size: 45 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DR3/LARD antibody - N-terminal (ab188628)Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human prostate tissue labelling DR3/LARD with ab188628 at 10µg/ml. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Protocols
Datasheets and documents
References (0)
ab188628 has not yet been referenced specifically in any publications.
