Anti-DR3/LARD antibody - N-terminal (ab188628)
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- References
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Overview
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Product name
Anti-DR3/LARD antibody - N-terminal
See all DR3/LARD primary antibodies -
Description
Rabbit polyclonal to DR3/LARD - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse
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Immunogen
Synthetic peptide corresponding to Human DR3/LARD aa 25-40 (N terminal).
Sequence:QGGTRS PRCDCAGDFH
Database link: Q93038 -
Positive control
- Jurkat cell lysate; Human prostate tissue.
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General notes
This product was previously labelled as DR3
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Ion Exchange Chromatography -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab188628 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/1000. Predicted molecular weight: 45 kDa. | |
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. -
Tissue specificity
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate. -
Sequence similarities
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
Post-translational
modificationsGlycosylated. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8718 Human
- Entrez Gene: 85030 Mouse
- Omim: 603366 Human
- SwissProt: Q93038 Human
- Unigene: 462529 Human
- Unigene: 101198 Mouse
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Alternative names
- Apo 3 antibody
- Apo-3 antibody
- Apo3 antibody
see all
Images
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Western blot - Anti-DR3/LARD antibody - N-terminal (ab188628)Anti-DR3/LARD antibody - N-terminal (ab188628) at 1/1000 dilution + Jurkat cell lysate
Predicted band size: 45 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DR3/LARD antibody - N-terminal (ab188628)Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human prostate tissue labelling DR3/LARD with ab188628 at 10µg/ml. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Datasheets and documents
References
ab188628 has not yet been referenced specifically in any publications.
