Overview

  • Product name
  • Description
    Rabbit polyclonal to DRAGON
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant fragment corresponding to Human DRAGON aa 219-467 (C terminal). NP_001012779

  • Positive control
    • 293T, HeLaS3, HepG2, Molt-4, Raji cell lysates. A431, H1299 whole cell lysates. U87 xenograft.
  • General notes

    Protein previously labeled as Repulsive Guidance Molecule B.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 1.21% Tris, 0.75% Glycine
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab96727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 52 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
  • Sequence similarities
    Belongs to the repulsive guidance molecule (RGM) family.
  • Post-translational
    modifications
    GPI-anchored.
  • Cellular localization
    Cell membrane. Membrane raft.
  • Information by UniProt
  • Database links
  • Alternative names
    • DRAGON antibody
    • DRG11-responsive axonal guidance and outgrowth of neurite antibody
    • Repulsive Guidance Molecule B antibody
    • RGM b antibody
    • RGM domain family member B antibody
    • Rgmb antibody
    • RGMB_HUMAN antibody
    see all

Images

  • All lanes : Anti-DRAGON antibody (ab96727) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa S3 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 52 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded U87 xenograft, using ab96727 at 1/100 dilution.

References

ab96727 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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