Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab121554 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|ICC/IF||Use a concentration of 1 - 4 µg/ml. Recommended fixation/permeabilization: PFA/Triton X-100|
FunctionInduces apoptotic cell death when co-expressed with DRAM1.
Tissue specificityExpression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Not detected in brain or thymus.
Sequence similaritiesBelongs to the DRAM/TMEM150 family.
Cellular localizationLysosome membrane.
- Information by UniProt
- 2010305N14Rik antibody
- 2610318G18Rik antibody
- AI647667 antibody
ab121554 at 1/100 dilution staining DRAM2 in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
Note: granular cytoplasmic positivity in glandular cells.
ab121554 at 4 µg/ml staining DRAM2 in PFA/Triton X-100 fixed/permeabilized U2 OS cells by Immunofluorescence (green).
Note: positivity in golgi apparatus & vesicles.
ab121554 has not yet been referenced specifically in any publications.