Overview

  • Product name

  • Description

    Rabbit polyclonal to Draxin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICCmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Chicken
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Draxin (C terminal) conjugated to keyhole limpet haemocyanin.

  • Positive control

    • Rat PC12 cells and cell lysate; Rat P1 brain, chick E9 brain and adult Mouse brain lysates.
  • General notes

    Do not aliquot.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.1% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab119707 was peptide affinity purified.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab119707 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 38 kDa).
ICC 1/100.

Target

  • Function

    Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
  • Sequence similarities

    Belongs to the draxin family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • AGPA3119 antibody
    • Chromosome 1 open reading frame 187 antibody
    • Dorsal inhibitory axon guidance protein antibody
    • Dorsal repulsive axon guidance protein antibody
    • DRAXI_HUMAN antibody
    • Draxin antibody
    • FLJ34999 antibody
    • MGC117222 antibody
    • Neucrin antibody
    • OTTHUMP00000002262 antibody
    • UNQ3119 antibody
    see all

Images

  • All lanes : Anti-Draxin antibody (ab119707) at 1/1000 dilution

    Lane 1 : Rat PC12 cell lysate
    Lane 2 : Rat P1 brain lysate
    Lane 3 : Adult mouse brain lysate
    Lane 4 : Chick E9 brain lysate

    Predicted band size: 38 kDa

  • ab119707 at 1/100 dilution staining Draxin in Rat PC12 cells, differentiated with NGF, by Immunocytochemistry in the absence (left) or presence (right) of blocking peptide. The lower images show corresponding phase images.
    detection used an appropriate secondary antibody conjugated to Cy3.

References

ab119707 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab119707.
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