Overview

  • Product name

  • Description

    Rabbit polyclonal to DRD4
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except HTR1D (65%).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Ferret, Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human DRD4 (C terminal).
    Database link: NP_000788.2

  • Positive control

    • Human brain (neurons and glia) tissue.
  • General notes

     This product was previously labelled as Dopamine Receptor D4

     

Properties

Applications

Our Abpromise guarantee covers the use of ab150576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications

    Polyubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex: polyubiquitination does not lead to degradation of DRD4 protein.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • D(2C) dopamine receptor antibody
    • D(4) dopamine receptor (D(2C) dopamine receptor). antibody
    • D(4) dopamine receptor antibody
    • D4 dopamine receptor antibody
    • D4DR antibody
    • Dopamine D4 receptor antibody
    • DRD 4 antibody
    • Drd4 antibody
    • DRD4_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin embedded Human brain (neurons and glia) tissue labeling DRD4 with ab150576 at 10µg/ml.

References

ab150576 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab150576.
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