Key features and details
- Rabbit polyclonal to DRD5 - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Product nameAnti-DRD5 antibody - C-terminal
See all DRD5 primary antibodies
DescriptionRabbit polyclonal to DRD5 - C-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat
- WB: Rat and mouse brain tissue lysates
This product was previously labelled as Dopamine Receptor D5
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab181623 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 53 kDa.|
FunctionDopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Tissue specificityNeuron-specific, localized primarily within limbic regions of the brain.
Involvement in diseaseDefects in DRD5 are a cause of benign essential blepharospasm (BEB) [MIM:606798]. BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- D(1B) dopamine receptor antibody
- D(5) dopamine receptor antibody
- D1 beta dopamine receptor antibody
All lanes : Anti-DRD5 antibody - C-terminal (ab181623) at 0.5 µg
Lane 1 : rat brain tissue
Lane 2 : mouse brain tissue
Lysates/proteins at 50 µg per lane.
All lanes : Goat anti-rabbit IgG-HRP at 1/10000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 53 kDa
ab181623 has not yet been referenced specifically in any publications.