Overview

  • Product name

  • Description

    Rabbit polyclonal to DRG1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Cow, Xenopus laevis, Zebrafish, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human DRG1 (internal sequence). The exact sequence is proprietary.
    Database link: Q9Y295

  • Positive control

    • WB: HEK-293T, A431, HeLa and HepG2 whole cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab229475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.

Target

  • Function

    May play a role in cell proliferation, differentiation and death.
  • Tissue specificity

    High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
  • Sequence similarities

    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • Domain

    Its C-terminal domain interacts with TAL1.
  • Post-translational
    modifications

    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
    Sumoylated by UBE2I in response to MEKK1-mediated stimuli.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Developmentally regulated GTP binding protein 1 antibody
    • Developmentally-regulated GTP-binding protein 1 antibody
    • DKFZp434N1827 antibody
    • DRG 1 antibody
    • DRG-1 antibody
    • DRG1 antibody
    • DRG1_HUMAN antibody
    • NEDD 3 antibody
    • NEDD-3 antibody
    • NEDD3 antibody
    • Neural precursor cell expressed developmentally down regulated protein 3 antibody
    • Neural precursor cell expressed developmentally down-regulated protein 3 antibody
    see all

Images

  • All lanes : Anti-DRG1 antibody (ab229475) at 1/1000 dilution

    Lane 1 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extracts
    Lane 2 : A431 (Human epidermoid carcinoma cell line) whole cell extracts
    Lane 3 : HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell extracts
    Lane 4 : HepG2 (Human liver hepatocellular carcinoma cell line) whole cell extracts

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 41 kDa



    10% SDS-PAGE gel.

References

ab229475 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229475.
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