Overview

  • Product name

    Anti-DRG1 antibody [EPR8465]
    See all DRG1 primary antibodies
  • Description

    Rabbit monoclonal [EPR8465] to DRG1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues near the C terminus of Human DRG1 (UniProt Q9Y295).

  • Positive control

    • K562, HeLa, 293T and Caco-2 cell lysates
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      May play a role in cell proliferation, differentiation and death.
    • Tissue specificity

      High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
    • Sequence similarities

      Belongs to the GTP1/OBG family.
      Contains 1 G (guanine nucleotide-binding) domain.
    • Domain

      Its C-terminal domain interacts with TAL1.
    • Post-translational
      modifications

      Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
      Sumoylated by UBE2I in response to MEKK1-mediated stimuli.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • Developmentally regulated GTP binding protein 1 antibody
      • Developmentally-regulated GTP-binding protein 1 antibody
      • DKFZp434N1827 antibody
      • DRG 1 antibody
      • DRG-1 antibody
      • DRG1 antibody
      • DRG1_HUMAN antibody
      • NEDD 3 antibody
      • NEDD-3 antibody
      • NEDD3 antibody
      • Neural precursor cell expressed developmentally down regulated protein 3 antibody
      • Neural precursor cell expressed developmentally down-regulated protein 3 antibody
      see all

    Images

    • All lanes : Anti-DRG1 antibody [EPR8465] (ab133648) at 1/1000 dilution

      Lane 1 : K562 cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : Caco-2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 41 kDa

    References

    ab133648 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133648.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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