Recombinant Anti-DRG1 antibody [EPR8465] (ab133648)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR8465] to DRG1
- Suitable for: WB
- Reacts with: Human
Overview
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Product name
Anti-DRG1 antibody [EPR8465]
See all DRG1 primary antibodies -
Description
Rabbit monoclonal [EPR8465] to DRG1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC,IHC-P or IP -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to residues near the C terminus of Human DRG1 (UniProt Q9Y295).
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Positive control
- K562, HeLa, 293T and Caco-2 cell lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR8465 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab133648 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 41 kDa. |
Target
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Function
May play a role in cell proliferation, differentiation and death. -
Tissue specificity
High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes. -
Sequence similarities
Belongs to the GTP1/OBG family.
Contains 1 G (guanine nucleotide-binding) domain. -
Domain
Its C-terminal domain interacts with TAL1. -
Post-translational
modificationsPolyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
Sumoylated by UBE2I in response to MEKK1-mediated stimuli. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 4733 Human
- Entrez Gene: 13494 Mouse
- Entrez Gene: 305470 Rat
- Omim: 603952 Human
- SwissProt: Q9Y295 Human
- SwissProt: P32233 Mouse
- Unigene: 115242 Human
- Unigene: 3250 Mouse
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Alternative names
- Developmentally regulated GTP binding protein 1 antibody
- Developmentally-regulated GTP-binding protein 1 antibody
- DKFZp434N1827 antibody
see all
Images
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All lanes : Anti-DRG1 antibody [EPR8465] (ab133648) at 1/1000 dilution
Lane 1 : K562 cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : 293T cell lysate
Lane 4 : Caco-2 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 41 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab133648 has not yet been referenced specifically in any publications.