RecombinantRabMAb

Recombinant Anti-DRG1 antibody [EPR8465] (ab133648)

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Western blot - Anti-DRG1 antibody [EPR8465] (ab133648)
  • Anti-DRG1 antibody [EPR8465] (ab133648)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR8465] to DRG1
  • Suitable for: WB
  • Reacts with: Human

Overview

  • Product name

    Anti-DRG1 antibody [EPR8465]
    See all DRG1 primary antibodies

  • Description

    Rabbit monoclonal [EPR8465] to DRG1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Synthetic peptide corresponding to residues near the C terminus of Human DRG1 (UniProt Q9Y295).

  • Positive control

    • K562, HeLa, 293T and Caco-2 cell lysates

  • General notes

     

     

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab133648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
Notes
WB
1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

    • Target

    • Function

      May play a role in cell proliferation, differentiation and death.

    • Tissue specificity

      High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.

    • Sequence similarities

      Belongs to the GTP1/OBG family.
      Contains 1 G (guanine nucleotide-binding) domain.

    • Domain

      Its C-terminal domain interacts with TAL1.

    • Post-translational
      modifications

      Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
      Sumoylated by UBE2I in response to MEKK1-mediated stimuli.

    • Cellular localization

      Cytoplasm.
    • Information by UniProt

    • Database links

      • Alternative names

        • Developmentally regulated GTP binding protein 1 antibody
        • Developmentally-regulated GTP-binding protein 1 antibody
        • DKFZp434N1827 antibody
        • DRG 1 antibody
        • DRG-1 antibody
        • DRG1 antibody
        • DRG1_HUMAN antibody
        • NEDD 3 antibody
        • NEDD-3 antibody
        • NEDD3 antibody
        • Neural precursor cell expressed developmentally down regulated protein 3 antibody
        • Neural precursor cell expressed developmentally down-regulated protein 3 antibody
        see all

      Images

      • Western blot - Anti-DRG1 antibody [EPR8465] (ab133648)
        Western blot - Anti-DRG1 antibody [EPR8465] (ab133648)
        All lanes : Anti-DRG1 antibody [EPR8465] (ab133648) at 1/1000 dilution

        Lane 1 : K562 cell lysate
        Lane 2 : HeLa cell lysate
        Lane 3 : 293T cell lysate
        Lane 4 : Caco-2 cell lysate

        Lysates/proteins at 10 µg per lane.

        Secondary
        All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

        Predicted band size: 41 kDa

      • Anti-DRG1 antibody [EPR8465] (ab133648)
        Anti-DRG1 antibody [EPR8465] (ab133648)

      References (0)

      Publishing research using ab133648? Please let us know so that we can cite the reference in this datasheet.

      ab133648 has not yet been referenced specifically in any publications.

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