Recombinant
RabMAb

Recombinant Anti-DRG1 antibody [EPR8465] (ab133648)

Submit a review Submit a question

Overview

  • Product name

    Anti-DRG1 antibody [EPR8465]
    See all DRG1 primary antibodies

  • Description

    Rabbit monoclonal [EPR8465] to DRG1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide corresponding to residues near the C terminus of Human DRG1 (UniProt Q9Y295).

  • Positive control

    • K562, HeLa, 293T and Caco-2 cell lysates

  • General notes

     

     

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Applications

Our Abpromise guarantee covers the use of ab133648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

    • Target

    • Function

      May play a role in cell proliferation, differentiation and death.

    • Tissue specificity

      High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.

    • Sequence similarities

      Belongs to the GTP1/OBG family.
      Contains 1 G (guanine nucleotide-binding) domain.

    • Domain

      Its C-terminal domain interacts with TAL1.

    • Post-translational
      modifications

      Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with ZC3H15.
      Sumoylated by UBE2I in response to MEKK1-mediated stimuli.

    • Cellular localization

      Cytoplasm.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • Developmentally regulated GTP binding protein 1 antibody
      • Developmentally-regulated GTP-binding protein 1 antibody
      • DKFZp434N1827 antibody
      • DRG 1 antibody
      • DRG-1 antibody
      • DRG1 antibody
      • DRG1_HUMAN antibody
      • NEDD 3 antibody
      • NEDD-3 antibody
      • NEDD3 antibody
      • Neural precursor cell expressed developmentally down regulated protein 3 antibody
      • Neural precursor cell expressed developmentally down-regulated protein 3 antibody
      see all

    Images

    • Western blot - Anti-DRG1 antibody [EPR8465] (ab133648)
      Western blot - Anti-DRG1 antibody [EPR8465] (ab133648)
      All lanes : Anti-DRG1 antibody [EPR8465] (ab133648) at 1/1000 dilution

      Lane 1 : K562 cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : 293T cell lysate
      Lane 4 : Caco-2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 41 kDa

    References

    ab133648 has not yet been referenced specifically in any publications.

    Publishing research using ab133648? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    There are currently no Customer reviews or Questions for ab133648.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com