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    drg2-antibody-ab121268.pdf

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Cell Biology Apoptosis Intracellular Associated Proteins
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Anti-DRG2 antibody (ab121268)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab121268)
  • Immunocytochemistry/ Immunofluorescence - Anti-DRG2 antibody (ab121268)

Key features and details

  • Rabbit polyclonal to DRG2
  • Suitable for: IHC-P, ICC/IF
  • Reacts with: Human
  • Isotype: IgG

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Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-DRG2 antibody
    See all DRG2 primary antibodies
  • Description

    Rabbit polyclonal to DRG2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    antigen, corresponding to amino acids 210-359 of Human DRG2 (P55039).

  • Positive control

    • Human kidney tissue, Human cell line U-2 OS
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cell Biology
    • Apoptosis
    • Intracellular
    • Associated Proteins
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • Small G Proteins
    • Other
    • Cell Biology
    • Cell Cycle
    • Cell differentiation

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab121268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6, using a pressure boiler
ICC/IF
Use a concentration of 0.25 - 2 µg/ml.
Notes
IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6, using a pressure boiler
ICC/IF
Use a concentration of 0.25 - 2 µg/ml.

Target

  • Function

    May play a role in cell proliferation, differentiation and death.
  • Tissue specificity

    Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
  • Sequence similarities

    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • Post-translational
    modifications

    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1.
  • Cellular localization

    Cytoplasm.
  • Target information above from: UniProt accession P55039 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 1819 Human
    • Omim: 602986 Human
    • SwissProt: P55039 Human
    • Unigene: 78582 Human
    • Alternative names

      • Developmentally regulated GTP binding protein 2 antibody
      • Developmentally-regulated GTP-binding protein 2 antibody
      • DRG 2 antibody
      • DRG-2 antibody
      • drg2 antibody
      • DRG2_HUMAN antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab121268)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab121268)
      ab121268 at 1/35 dilution staining DRG2 in Human kidney by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
    • Immunocytochemistry/ Immunofluorescence - Anti-DRG2 antibody (ab121268)
      Immunocytochemistry/ Immunofluorescence - Anti-DRG2 antibody (ab121268)
      ab121268 at 4 µg/ml staining DRG2 in Human cell line U-2 OS by Immunofluorescent staining. Antibody staining is shown in green.

    Protocols

    • Immunohistochemistry protocols
    • Immunocytochemistry & immunofluorescence protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab121268? Please let us know so that we can cite the reference in this datasheet.

    ab121268 has not yet been referenced specifically in any publications.

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