Anti-DRG2 antibody (ab121268)
Key features and details
- Rabbit polyclonal to DRG2
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DRG2 antibody
See all DRG2 primary antibodies -
Description
Rabbit polyclonal to DRG2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen, corresponding to amino acids 210-359 of Human DRG2 (P55039).
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Positive control
- Human kidney tissue, Human cell line U-2 OS
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab121268 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6, using a pressure boiler
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| ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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| Notes |
|---|
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IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6, using a pressure boiler |
|
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
Target
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Function
May play a role in cell proliferation, differentiation and death. -
Tissue specificity
Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes. -
Sequence similarities
Belongs to the GTP1/OBG family.
Contains 1 G (guanine nucleotide-binding) domain. -
Post-translational
modificationsPolyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 1819 Human
- Omim: 602986 Human
- SwissProt: P55039 Human
- Unigene: 78582 Human
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Alternative names
- Developmentally regulated GTP binding protein 2 antibody
- Developmentally-regulated GTP-binding protein 2 antibody
- DRG 2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab121268)ab121268 at 1/35 dilution staining DRG2 in Human kidney by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
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Immunocytochemistry/ Immunofluorescence - Anti-DRG2 antibody (ab121268)ab121268 at 4 µg/ml staining DRG2 in Human cell line U-2 OS by Immunofluorescent staining. Antibody staining is shown in green.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab121268 has not yet been referenced specifically in any publications.