Overview

  • Product name
    Anti-DRG2 antibody
    See all DRG2 primary antibodies
  • Description
    Rabbit polyclonal to DRG2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen, corresponding to amino acids 210-359 of Human DRG2 (P55039).

  • Positive control
    • Human kidney tissue, Human cell line U-2 OS

Properties

Applications

Our Abpromise guarantee covers the use of ab121268 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6, using a pressure boiler
ICC/IF Use a concentration of 1 - 4 µg/ml. The following steps are recommended prior to antibody incubation: cells fixation in ice cold 4% paraformaldehyde pH 7.2-7.3, followed by permeabilization with 0.1% Triton X-100 in PBS for 3x5 minutes.

Target

  • Function
    May play a role in cell proliferation, differentiation and death.
  • Tissue specificity
    Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
  • Sequence similarities
    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • Post-translational
    modifications
    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
    • Alternative names
      • Developmentally regulated GTP binding protein 2 antibody
      • Developmentally-regulated GTP-binding protein 2 antibody
      • DRG 2 antibody
      • DRG-2 antibody
      • drg2 antibody
      • DRG2_HUMAN antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab121268)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab121268)
      ab121268 at 1/35 dilution staining DRG2 in Human kidney by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
    • Immunocytochemistry/ Immunofluorescence - Anti-DRG2 antibody (ab121268)
      Immunocytochemistry/ Immunofluorescence - Anti-DRG2 antibody (ab121268)
      ab121268 at 4 µg/ml staining DRG2 in Human cell line U-2 OS by Immunofluorescent staining. Antibody staining is shown in green.

    References

    ab121268 has not yet been referenced specifically in any publications.

    Publishing research using ab121268? Please let us know so that we can cite the reference in this datasheet.

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