Anti-DRG2 antibody (ab127170)
Key features and details
- Rabbit polyclonal to DRG2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DRG2 antibody
See all DRG2 primary antibodies -
Description
Rabbit polyclonal to DRG2 -
Host species
Rabbit -
Tested Applications & Species
Application Species IHC-P HumanWB Human -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 55 - 273 of Human DRG2
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Positive control
- Jurkat and 293T whole cell lysates Lung cancer tissue
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab127170 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
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IHC-P |
Human
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WB |
Human
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Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
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|
IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Alternatively Tris-EDTA buffer ( pH8.0) may be used.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 41 kDa. |
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Alternatively Tris-EDTA buffer ( pH8.0) may be used. |
Target
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Function
May play a role in cell proliferation, differentiation and death. -
Tissue specificity
Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes. -
Sequence similarities
Belongs to the GTP1/OBG family.
Contains 1 G (guanine nucleotide-binding) domain. -
Post-translational
modificationsPolyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 1819 Human
- Omim: 602986 Human
- SwissProt: P55039 Human
- Unigene: 78582 Human
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Alternative names
- Developmentally regulated GTP binding protein 2 antibody
- Developmentally-regulated GTP-binding protein 2 antibody
- DRG 2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab127170)ab127170, at 1/500 dilution, staining Human DRG2 in paraffin-embedded lung cancer tissue by immunohistochemistry
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Anti-DRG2 antibody (ab127170) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg
Predicted band size: 41 kDa
10% SDS PAGE
Protocols
References (0)
ab127170 has not yet been referenced specifically in any publications.