Overview

  • Product name

  • Description

    Rabbit polyclonal to DRG2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 55 - 273 of Human DRG2

  • Positive control

    • Jurkat and 293T whole cell lysates Lung cancer tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab127170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 41 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Alternatively Tris-EDTA buffer ( pH8.0) may be used.

Target

  • Function

    May play a role in cell proliferation, differentiation and death.
  • Tissue specificity

    Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.
  • Sequence similarities

    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • Post-translational
    modifications

    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Developmentally regulated GTP binding protein 2 antibody
    • Developmentally-regulated GTP-binding protein 2 antibody
    • DRG 2 antibody
    • DRG-2 antibody
    • drg2 antibody
    • DRG2_HUMAN antibody
    see all

Images

  • ab127170, at 1/500 dilution, staining Human DRG2 in paraffin-embedded lung cancer tissue by immunohistochemistry
  • Anti-DRG2 antibody (ab127170) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

    Predicted band size: 41 kDa



    10% SDS PAGE

References

ab127170 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab127170.
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