Anti-DRG2 antibody (ab127170)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-DRG2 antibody
See all DRG2 primary antibodies -
Description
Rabbit polyclonal to DRG2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 55 - 273 of Human DRG2
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Positive control
- Jurkat and 293T whole cell lysates Lung cancer tissue
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78% PBS, 1% BSA, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab127170 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 41 kDa. | |
| IHC-P | 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Alternatively Tris-EDTA buffer ( pH8.0) may be used. |
Target
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Function
May play a role in cell proliferation, differentiation and death. -
Tissue specificity
Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes. -
Sequence similarities
Belongs to the GTP1/OBG family.
Contains 1 G (guanine nucleotide-binding) domain. -
Post-translational
modificationsPolyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 1819 Human
- Omim: 602986 Human
- SwissProt: P55039 Human
- Unigene: 78582 Human
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Alternative names
- Developmentally regulated GTP binding protein 2 antibody
- Developmentally-regulated GTP-binding protein 2 antibody
- DRG 2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab127170)ab127170, at 1/500 dilution, staining Human DRG2 in paraffin-embedded lung cancer tissue by immunohistochemistry -
Western blot - Anti-DRG2 antibody (ab127170)Anti-DRG2 antibody (ab127170) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg
Predicted band size: 41 kDa
10% SDS PAGE
References
ab127170 has not yet been referenced specifically in any publications.
