Anti-DRG2 antibody (ab127170)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab127170)
  • Western blot - Anti-DRG2 antibody (ab127170)

Key features and details

  • Rabbit polyclonal to DRG2
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

Overview

  • Product name

    Anti-DRG2 antibody
    See all DRG2 primary antibodies

  • Description

    Rabbit polyclonal to DRG2

  • Host species

    Rabbit

  • Tested Applications & Species

    Application Species
    IHC-P
    Human
    WB
    Human
    See all applications and species data

  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 55 - 273 of Human DRG2

  • Positive control

    • Jurkat and 293T whole cell lysates Lung cancer tissue

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab127170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Guaranteed

Tested applications are guaranteed to work and covered by our Abpromise guarantee.

Predicted

Predicted to work for this combination of applications and species but not guaranteed.

Incompatible

Does not work for this combination of applications and species.

Application Species
IHC-P
Human
WB
Human
Application Abreviews Notes
WB
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Alternatively Tris-EDTA buffer ( pH8.0) may be used.
Notes
WB
1/500 - 1/3000. Predicted molecular weight: 41 kDa.
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Alternatively Tris-EDTA buffer ( pH8.0) may be used.

Target

  • Function

    May play a role in cell proliferation, differentiation and death.

  • Tissue specificity

    Highest levels in skeletal muscle, heart and kidney. Low levels in colon, thymus, spleen, small intestine, lung and Leukocytes.

  • Sequence similarities

    Belongs to the GTP1/OBG family.
    Contains 1 G (guanine nucleotide-binding) domain.

  • Post-translational
    modifications

    Polyubiquitinated; which induces proteolytic degradation and is impaired by interaction with RWDD1.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

  • Database links

    • Alternative names

      • Developmentally regulated GTP binding protein 2 antibody
      • Developmentally-regulated GTP-binding protein 2 antibody
      • DRG 2 antibody
      • DRG-2 antibody
      • drg2 antibody
      • DRG2_HUMAN antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab127170)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DRG2 antibody (ab127170)
      ab127170, at 1/500 dilution, staining Human DRG2 in paraffin-embedded lung cancer tissue by immunohistochemistry
    • Western blot - Anti-DRG2 antibody (ab127170)
      Western blot - Anti-DRG2 antibody (ab127170)
      Anti-DRG2 antibody (ab127170) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

      Predicted band size: 41 kDa



      10% SDS PAGE

    References (0)

    Publishing research using ab127170? Please let us know so that we can cite the reference in this datasheet.

    ab127170 has not yet been referenced specifically in any publications.

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