Overview

  • Product name

  • Description

    Rabbit polyclonal to DRIP130
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human DRIP130 (internal sequence). The exact sequence is proprietary.
    Database link: Q9ULK4

  • Positive control

    • A549 cell extracts; A549 cells; Human colon carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab196752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
WB 1/500 - 1/3000. Predicted molecular weight: 156 kDa.
ICC/IF 1/100 - 1/500.

Target

  • Function

    Required for transcriptional activation subsequent to the assembly of the preinitiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
  • Sequence similarities

    Belongs to the Mediator complex subunit 23 family.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • 130 kDa transcriptional co activator antibody
    • 133 kDa transcriptional co activator antibody
    • Activator recruited cofactor 130 kDa component antibody
    • Activator-recruited cofactor 130 kDa component antibody
    • ARC 130 antibody
    • ARC130 antibody
    • Cofactor required for Sp1 transcriptional activation subunit 3 130kDa antibody
    • Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator antibody
    • Cofactor required for Sp1 transcriptional activation subunit 3 antibody
    • CRSP 130 antibody
    • CRSP 130 kD subunit antibody
    • CRSP 133 antibody
    • CRSP 3 antibody
    • CRSP complex subunit 3 antibody
    • CRSP130 antibody
    • CRSP133 antibody
    • CRSP3 antibody
    • CRSP3 protein antibody
    • DKFZp434H0117 antibody
    • DRIP 130 antibody
    • DRIP130 antibody
    • hSur-2 antibody
    • KIAA1216 antibody
    • MED 23 antibody
    • med23 antibody
    • MED23_HUMAN antibody
    • Mediator complex subunit 23 antibody
    • Mediator of RNA polymerase II transcription subunit 23 antibody
    • MRT18 antibody
    • Protein sur-2 homolog antibody
    • SUR 2 antibody
    • SUR2 antibody
    • Transcriptional co activator CRSP 130 antibody
    • Transcriptional co activator CRSP130 antibody
    • Transcriptional coactivator CRSP130 antibody
    • Vitamin D3 receptor interacting protein antibody
    • Vitamin D3 receptor interacting protein complex 130 kDa component antibody
    • Vitamin D3 receptor-interacting protein complex 130 kDa component antibody
    see all

Images

  • All lanes : Anti-DRIP130 antibody (ab196752) at 1/500 dilution

    Lane 1 : A549 cell extracts
    Lane 2 : A549 cell extracts with Immunizing peptide

    Predicted band size: 156 kDa

  • Immunohistochemical analysis of paraffin-embedded Human colon carcinoma tissue labeling DRIP130 with ab196752 at a 1/50 dilution. The image on the right was treated with the synthesized peptide.

  • Immunofluorescent analysis of A549 cells labeling DRIP130 with ab196752 at a 1/100 dilution. The image on the right was treated with the synthesized peptide.

References

ab196752 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab196752.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up