Key features and details
- Rabbit polyclonal to DRIP130
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DRIP130 antibody
See all DRIP130 primary antibodies
DescriptionRabbit polyclonal to DRIP130
Tested applicationsSuitable for: IPmore details
Unsuitable for: WB
Species reactivityReacts with: Human
Predicted to work with: Mouse, Horse, Guinea pig, Dog, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Orangutan, Zebra finch
Synthetic peptide, corresponding to a region between amino acids 400-450 of Human DRIP130 (SwissProt Q9ULK4)
- Nuclear extract from HeLa cells
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab70449 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Is unsuitable for WB.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionRequired for transcriptional activation subsequent to the assembly of the preinitiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
Sequence similaritiesBelongs to the Mediator complex subunit 23 family.
- Information by UniProt
- 130 kDa transcriptional co activator antibody
- 133 kDa transcriptional co activator antibody
- Activator recruited cofactor 130 kDa component antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab70449 has been referenced in 1 publication.
- Meyer KD et al. Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. EMBO J 27:1447-57 (2008). PubMed: 18418385