Overview

  • Product name

    Drospirenone, synthetic progestin
  • Description

    Synthetic progestin. Spironolactone analog. Potent antimineralocorticoid agent.
  • Biological description

    Synthetic progestin. Spironolactone (ab141289) analog. Potent antimineralocorticoid agent. Counteracts estrogen-induced stimulation of the renin-angiotensin-aldosterone system. Blocks testosterone binding to androgen receptors. Shows progesteronic effects in vivo. Orally active.
  • CAS Number

    67392-87-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zhang Y  et al. Preparation and evaluation of intravaginal ring containing drospirenone. Adv Pharmacol Sci 2013:192408 (2013). Read more (PubMed: 23401679) »
  • van Diepen HA  et al. Nomegestrol acetate: steroid receptor transactivation profile in Chinese hamster ovary cells and ovulation inhibition in rat and monkey. Contraception 84:199-204 (2011). Read more (PubMed: 21757063) »
  • Koitka M  et al. Improving the ex vivo stability of drug ester compounds in rat and dog serum: inhibition of the specific esterases and implications on their identity. J Pharm Biomed Anal 51:664-78 (2010). Read more (PubMed: 19850433) »

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