Anti-ds DNA antibody [SPM603] (ab270736)

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Key features and details

  • Mouse monoclonal [SPM603] to ds DNA
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG3

Overview

  • Product name

    Anti-ds DNA antibody [SPM603]
    See all ds DNA primary antibodies

  • Description

    Mouse monoclonal [SPM603] to ds DNA

  • Host species

    Mouse

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Tissue, cells or virus corresponding to Human ds DNA. Nuclei of Burkitt's cells

  • Positive control

    • IHC-P: Human tonsil tissue.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: PBS, 0.05% BSA
  • Concentration information loading...

  • Purification notes

    Purified from Bioreactor Concentrate.

  • Clonality

    Monoclonal

  • Clone number

    SPM603

  • Isotype

    IgG3

  • Light chain type

    kappa

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab270736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Target

  • Relevance

    dsDNA (double stranded deoxyribonucleic acid) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.

  • Cellular localization

    Nuclear

  • Alternative names

    • Double stranded deoxyribonucleic acid antibody
    • Double stranded DNA antibody
    • dsDNA antibody

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [SPM603] (ab270736)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ds DNA antibody [SPM603] (ab270736)

    Formalin-fixed, paraffin-embedded human tonsil tissue stained for ds DNA using ab270736 at 2 µg/ml in immunohistochemical analysis.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab270736? Please let us know so that we can cite the reference in this datasheet.

ab270736 has not yet been referenced specifically in any publications.

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