Overview

  • Product name

    Anti-DSCAML1 antibody [DS1-96]
    See all DSCAML1 primary antibodies
  • Description

    Mouse monoclonal [DS1-96] to DSCAML1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, IHC-FoFrmore details
  • Species reactivity

    Reacts with: Mouse, Chicken
  • Immunogen

    An epitope located within the C terminal region of Chicken DSCAML1 (amino acids 761 to 1072).

  • Positive control

    • Transfected Human embryonic kidney 293 cells overexpressing mouse DSCAML1.

Properties

Applications

Our Abpromise guarantee covers the use of ab150761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 224 kDa.
IHC-FoFr Use a concentration of 5 - 10 µg/ml. Tissue was fixed with 4% paraformaldehyde/PBS.

Target

  • Function

    Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells.
  • Tissue specificity

    Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.
  • Sequence similarities

    Contains 6 fibronectin type-III domains.
    Contains 10 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Down syndrome cell adhesion molecule 2 antibody
    • Down syndrome cell adhesion molecule like 1 antibody
    • Down syndrome cell adhesion molecule like protein 1 antibody
    • Down syndrome cell adhesion molecule-like protein 1 antibody
    • DSCAM2 antibody
    • DSCAML1 antibody
    • DSCL1_HUMAN antibody
    see all

Images

  • Immunocytochemistry/immunofluorescence analysis of transfected human embryonic kidney 293 cells overexpressing mouse DSCAML1. Cells were fixed with 4% paraformaldehyde in PBS. Cells were labelled with ab150761.

References

ab150761 has not yet been referenced specifically in any publications.

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