Overview

  • Product name

    Anti-DTX3 antibody - C-terminal
  • Description

    Rabbit polyclonal to DTX3 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Fusion protein corresponding to Human DTX3 (C terminal). (BC114498).
    Database link: Q8N9I9

  • Positive control

    • Human tonsil tissue; SKOV3 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab197360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/100.
WB 1/200 - 1/1000. Predicted molecular weight: 38 kDa.

Target

  • Function

    Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
  • Sequence similarities

    Belongs to the Deltex family.
    Contains 1 RING-type zinc finger.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Deltex3 antibody
    • Dtx3 antibody
    • DTX3_HUMAN antibody
    • Protein deltex 3 antibody
    • Protein deltex-3 antibody
    • RING finger protein 154 antibody
    • RNF154 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human tonsil tissue labeling DTX3 with ab197360 at 1/20 dilution.

  • Anti-DTX3 antibody - C-terminal (ab197360) at 1/200 dilution + SKOV3 cell lysate at 40 µg

    Developed using the ECL technique.

    Predicted band size: 38 kDa


    Exposure time: 10 minutes


    Gel: 10%SDS-PAGE.

     

References

ab197360 has not yet been referenced specifically in any publications.

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