Overview

  • Product name

    Anti-DTX4 antibody - C-terminal
    See all DTX4 primary antibodies
  • Description

    Rabbit polyclonal to DTX4 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 570-619 of Human DTX4 (NP_055992).

  • Positive control

    • Human fetal liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab140289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 67 kDa.

Target

  • Function

    Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as an ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Belongs to the Deltex family.
    Contains 1 RING-type zinc finger.
    Contains 2 WWE domains.
  • Domain

    The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Deltex4 antibody
    • Dtx4 antibody
    • DTX4_HUMAN antibody
    • E3 ubiquitin-protein ligase DTX4 antibody
    • Protein deltex-4 antibody
    • RING finger protein 155 antibody
    • RNF155 antibody
    see all

Images

  • Anti-DTX4 antibody - C-terminal (ab140289) at 1 µg/ml + Huma fetal liver lysate at 10 µg

    Predicted band size: 67 kDa

References

ab140289 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab140289.
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