Key features and details
- Dual color: FITC + PE Rat monoclonal [YKIX 302.9 + YCATE 55.9] to CD4 + CD8
- Suitable for: Flow Cyt
- Reacts with: Dog
- Conjugation: Dual color: FITC + PE
Product nameDual color: FITC + PE Anti-CD4 + CD8 antibody [YKIX 302.9 + YCATE 55.9]
See all CD4 + CD8 primary antibodies
DescriptionDual color: FITC + PE Rat monoclonal [YKIX 302.9 + YCATE 55.9] to CD4 + CD8
ConjugationDual color: FITC + PE
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Dog
This product was produced with the following immunogens:
Tissue, cells or virus. Concanavallin A activated T cell blasts. (CloneYKIX302.9)
Fusion protein. CD8 alpha chimaeric human IgG1 Fc fusion protein. (Clone YCATE55.9)
Please note that this antibody is an oligoclonal antibody. It is a cocktail of monoclonal antibodies that have been carefully selected. Oligoclonal antibodies have not only the specificity and batch-to-batch consistency of a monoclonal antibody, but also have the advantage of the sensitivity of a polyclonal antibody due to their ability to recognize multiple epitopes on an antigen. This cocktail consists of: CD4 = Clone:YKIX 302.9, Isotype:IgG1, Label:FITC CD8 = Clone:YCATE 55.9, Isotype:IgG2a, Label:PE
ab34267 should be stored undiluted. It is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C. Do Not Freeze. Please see notes section.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, PBS, 5% Sucrose
Concentration information loading...
PurityProtein G purified
Clone numberYKIX 302.9 + YCATE 55.9
Our Abpromise guarantee covers the use of ab34267 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 10µl for 106 cells.|
RelevanceCD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Cellular localizationMembrane; single pass type I membrane protein.
- CD4 antigen antibody
- CD4 molecule antibody
- CD4 mut antibody
ab34267 has not yet been referenced specifically in any publications.