Anti-DUOX1 antibody (ab78919)
Key features and details
- Goat polyclonal to DUOX1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-DUOX1 antibody
See all DUOX1 primary antibodies -
Description
Goat polyclonal to DUOX1 -
Host species
Goat -
Specificity
This antibody is expected to recognise both reported isoforms (NP_059130.2 ; NP_787954.1) which are identical. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human DUOX1 aa 1020-1032 (internal sequence). Synthetic peptide:
EKFQRSCLHQTVQ
, corresponding to internal sequence amino acids 1020-1032 of Human DUOX1 (NP_059130.2 ; NP_787954.1)
Sequence:EKFQRSCLHQTVQ
Database link: Q9NRD9 -
Positive control
- Human placenta and thyroid gland lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab78919 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 4 - 6 µg/ml.
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Notes |
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IHC-P
Use a concentration of 4 - 6 µg/ml. |
Target
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Relevance
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene). -
Cellular localization
Cell Membrane -
Database links
- Entrez Gene: 53905 Human
- Omim: 606758 Human
- SwissProt: Q9NRD9 Human
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Alternative names
- Dual oxidase 1 antibody
- Dual oxidase 1 precursor antibody
- DUOX1 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab78919 has been referenced in 1 publication.
- Yang N et al. LincRNA-p21 activates endoplasmic reticulum stress and inhibits hepatocellular carcinoma. Oncotarget 6:28151-63 (2015). WB . PubMed: 26305675