• Product name

  • Description

    Goat polyclonal to DUOX1
  • Host species

  • Specificity

    This antibody is expected to recognise both reported isoforms (NP_059130.2 ; NP_787954.1) which are identical.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human DUOX1 aa 1020-1032 (internal sequence). Synthetic peptide:


    , corresponding to internal sequence amino acids 1020-1032 of Human DUOX1 (NP_059130.2 ; NP_787954.1)


    Database link: Q9NRD9

  • Positive control

    • Human placenta and thyroid gland lysates.



Our Abpromise guarantee covers the use of ab78919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 6 µg/ml.


  • Relevance

    The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene (from EntrezGene).
  • Cellular localization

    Cell Membrane
  • Database links

  • Alternative names

    • Dual oxidase 1 antibody
    • Dual oxidase 1 precursor antibody
    • DUOX1 antibody
    • EC 1.11.1 antibody
    • EC antibody
    • Flavoprotein NADPH oxidase antibody
    • Large NOX 1 antibody
    • LNOX1 antibody
    • Long NOX 1 antibody
    • MGC138840 antibody
    • MGC138841 antibody
    • NADPH thyroid oxidase 1 antibody
    • Nicotinamide adenine dinucleotide phosphate oxidase antibody
    • NOXEF1 antibody
    • THOX1 antibody
    • Thyroid oxidase 1 antibody
    see all


  • Immunohistochemical analysis of paraffin embedded Human thyroid gland labeling DUOX1 with ab78919 at 4-6μg/ml. The image shows staining of membranes in epithelial cells of the thyroid gland.

    Steamed antigen retrieval with Tris/EDTA buffer pH 9 was performed. Antibody was detected by HRP-staining.


This product has been referenced in:

  • Yang N  et al. LincRNA-p21 activates endoplasmic reticulum stress and inhibits hepatocellular carcinoma. Oncotarget 6:28151-63 (2015). WB . Read more (PubMed: 26305675) »
See 1 Publication for this product

Customer reviews and Q&As


Thank you for contacting us.

As you may know, ab78919 is one of our Fast-track antibodies and it is not yet fully characterized. We cannot guarantee that the antibody will work in any application other than ELISA against the immunizing peptide and are therefore unable to offer a replacement, credit or refund if the antibody does not work in your application. Due to this, Fast-Track antibodies are offered at a reduced price.

We would greatly appreciate your feedback on these antibodies, whether positive or negative. We have a special feedback reward system for Fast-track products: we will award 950 Abpoints to the first researcher who sends us positive feedback (including an image and details of your protocol). Conclusive negative feedback that leads us to withdraw the antibody will also be rewarded with 950 Abpoints.

Other useful positive and negative feedback will be rewarded with the standard amount of Abpoints for submitting an Abreview (please refer to Abreviews terms and conditions for more detailed information, see https://www.abcam.com/abreviews). All awards are subject to approval by Abcam scientists and provision of suitable data. Please submit feedback to fast-track@abcam.com.

I hope this information has been helpful to you. We greatly appreciate any feedback you can provide.

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